β-Adrenergic receptors control brown adipose UCP-1 tone and cold response without affecting its circadian rhythmicity.
Razzoli M, Emmett MJ, Lazar MA, Bartolomucci A.
Razzoli M, et al.
FASEB J. 2018 Oct;32(10):5640-5646. doi: 10.1096/fj.201800452R. Epub 2018 May 1.
FASEB J. 2018.
PMID: 29715048
Free PMC article.
Our results demonstrate that in addition to controlling the BAT response to extreme cold, betaAR signaling is necessary to maintain basal Ucp1 tone and to couple BAT circadian rhythmicity to the central clock.-Razzoli, M., Emmett, M. J., Lazar, M. A., …
Our results demonstrate that in addition to controlling the BAT response to extreme cold, betaAR signaling is necessary to maintain basal Uc …