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An engineered ligand trap inhibits leukemia inhibitory factor as pancreatic cancer treatment strategy.
Commun Biol. 2021 Apr 12;4(1):452. doi: 10.1038/s42003-021-01928-2.
Commun Biol. 2021.
PMID: 33846527
Free PMC article.
Engineering a potent receptor superagonist or antagonist from a novel IL-6 family cytokine ligand.
Kim JW, Marquez CP, Sperberg RAP, Wu J, Bae WG, Huang PS, Sweet-Cordero EA, Cochran JR.
Kim JW, et al. Among authors: sperberg rap.
Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14110-14118. doi: 10.1073/pnas.1922729117. Epub 2020 Jun 10.
Proc Natl Acad Sci U S A. 2020.
PMID: 32522868
Free PMC article.
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Identification of N-Terminally Diversified GLP-1R Agonists Using Saturation Mutagenesis and Chemical Design.
Longwell CK, Hanna S, Hartrampf N, Sperberg RAP, Huang PS, Pentelute BL, Cochran JR.
Longwell CK, et al. Among authors: sperberg rap.
ACS Chem Biol. 2021 Jan 15;16(1):58-66. doi: 10.1021/acschembio.0c00722. Epub 2020 Dec 14.
ACS Chem Biol. 2021.
PMID: 33307682
Free PMC article.
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Theoretical basis for stabilizing messenger RNA through secondary structure design.
Wayment-Steele HK, Kim DS, Choe CA, Nicol JJ, Wellington-Oguri R, Watkins AM, Sperberg RAP, Huang PS, Participants E, Das R.
Wayment-Steele HK, et al. Among authors: sperberg rap.
bioRxiv [Preprint]. 2021 Feb 19:2020.08.22.262931. doi: 10.1101/2020.08.22.262931.
bioRxiv. 2021.
PMID: 32869022
Free PMC article.
Updated.
Preprint.
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A general platform for targeting MHC-II antigens via a single loop.
Du H, Liu J, Jude KM, Yang X, Li Y, Bell B, Yang H, Kassardjian A, Mobedi A, Parekh U, Sperberg RAP, Julien JP, Mellins ED, Garcia KC, Huang PS.
Du H, et al. Among authors: sperberg rap.
bioRxiv [Preprint]. 2024 Jan 30:2024.01.26.577489. doi: 10.1101/2024.01.26.577489.
bioRxiv. 2024.
PMID: 38352315
Free PMC article.
Preprint.
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