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Oncogenic Rag GTPase signaling enhances B cell activation and drives follicular lymphoma sensitive to pharmacological inhibition of mTOR.
Ortega-Molina A, Deleyto-Seldas N, Carreras J, Sanz A, Lebrero-Fernández C, Menéndez C, Vandenberg A, Fernández-Ruiz B, Marín-Arraiza L, de la Calle Arregui C, Belén Plata-Gómez A, Caleiras E, de Martino A, Martínez-Martín N, Troulé K, Piñeiro-Yáñez E, Nakamura N, Araf S, Victora GD, Okosun J, Fitzgibbon J, Efeyan A. Ortega-Molina A, et al. Among authors: sanz a. Nat Metab. 2019 Aug;1(8):775-789. doi: 10.1038/s42255-019-0098-8. Epub 2019 Aug 19. Nat Metab. 2019. PMID: 31579886 Free PMC article.
Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3' untranslated region.
Fernández LP, Deleyto-Seldas N, Colmenarejo G, Sanz A, Wagner S, Plata-Gómez AB, Gómez-Patiño M, Molina S, Espinosa-Salinas I, Aguilar-Aguilar E, Ortega S, Graña-Castro O, Loria-Kohen V, Fernández-Marcos PJ, Efeyan A, Ramírez de Molina A. Fernández LP, et al. Among authors: sanz a. Genome Biol. 2022 Oct 31;23(1):230. doi: 10.1186/s13059-022-02798-5. Genome Biol. 2022. PMID: 36316722 Free PMC article.
NGFR regulates stromal cell activation in germinal centers.
Hernández-Barranco A, Santos V, Mazariegos MS, Caleiras E, Nogués L, Mourcin F, Léonard S, Oblet C, Genebrier S, Rossille D, Benguría A, Sanz A, Vázquez E, Dopazo A, Efeyan A, Ortega-Molina A, Cogne M, Tarte K, Peinado H. Hernández-Barranco A, et al. Among authors: sanz a. Cell Rep. 2024 Feb 27;43(2):113705. doi: 10.1016/j.celrep.2024.113705. Epub 2024 Feb 1. Cell Rep. 2024. PMID: 38307025 Free article.
Hepatic nutrient and hormone signaling to mTORC1 instructs the postnatal metabolic zonation of the liver.
Plata-Gómez AB, de Prado-Rivas L, Sanz A, Deleyto-Seldas N, García F, de la Calle Arregui C, Silva C, Caleiras E, Graña-Castro O, Piñeiro-Yáñez E, Krebs J, Leiva-Vega L, Muñoz J, Jain A, Sabio G, Efeyan A. Plata-Gómez AB, et al. Among authors: sanz a. Nat Commun. 2024 Mar 18;15(1):1878. doi: 10.1038/s41467-024-46032-1. Nat Commun. 2024. PMID: 38499523 Free PMC article.
Sphingosine kinase 1 overexpression induces MFN2 fragmentation and alters mitochondrial matrix Ca2+ handling in HeLa cells.
Pulli I, Löf C, Blom T, Asghar MY, Lassila T, Bäck N, Lin KL, Nyström JH, Kemppainen K, Toivola DM, Dufour E, Sanz A, Cooper HM, Parys JB, Törnquist K. Pulli I, et al. Among authors: sanz a. Biochim Biophys Acta Mol Cell Res. 2019 Sep;1866(9):1475-1486. doi: 10.1016/j.bbamcr.2019.06.006. Epub 2019 Jun 17. Biochim Biophys Acta Mol Cell Res. 2019. PMID: 31220477 Free article.
Diagnostic yield of bone marrow aspiration in paediatric primary immune thrombocytopenia: impact of evolution and adherence to medical guidelines over the last 25 years.
de Pablo JG, Zubicaray J, Iriondo J, Pérez Maroto F, Azorín D, de la Cruz Benito A, Sanz A, Madero L, González-Vicent M, Sevilla J, Sebastián E. de Pablo JG, et al. Among authors: sanz a. Eur J Pediatr. 2024 May 21. doi: 10.1007/s00431-024-05583-7. Online ahead of print. Eur J Pediatr. 2024. PMID: 38771372
Tenecteplase versus standard of care for minor ischaemic stroke with proven occlusion (TEMPO-2): a randomised, open label, phase 3 superiority trial.
Coutts SB, Ankolekar S, Appireddy R, Arenillas JF, Assis Z, Bailey P, Barber PA, Bazan R, Buck BH, Butcher KS, Camden MC, Campbell B, Casaubon LK, Catanese L, Chatterjee K, Choi PMC, Clarke B, Dowlatshahi D, Ferrari J, Field TS, Ganesh A, Ghia D, Goyal M, Greisenegger S, Halse O, Horn M, Hunter G, Imoukhuede O, Kelly PJ, Kennedy J, Kenney C, Kleinig TJ, Krishnan K, Lima F, Mandzia JL, Marko M, Martins SO, Medvedev G, Menon BK, Mishra SM, Molina C, Moussaddy A, Muir KW, Parsons MW, Penn AMW, Pille A, Pontes-Neto OM, Roffe C, Serena J, Simister R, Singh N, Spratt N, Strbian D, Tham CH, Wiggam MI, Williams DJ, Willmot MR, Wu T, Yu AYX, Zachariah G, Zafar A, Zerna C, Hill MD; TEMPO-2 investigators. Coutts SB, et al. Lancet. 2024 May 16:S0140-6736(24)00921-8. doi: 10.1016/S0140-6736(24)00921-8. Online ahead of print. Lancet. 2024. PMID: 38768626
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