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Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq.
Replogle JM, Saunders RA, Pogson AN, Hussmann JA, Lenail A, Guna A, Mascibroda L, Wagner EJ, Adelman K, Lithwick-Yanai G, Iremadze N, Oberstrass F, Lipson D, Bonnar JL, Jost M, Norman TM, Weissman JS. Replogle JM, et al. Among authors: adelman k. Cell. 2022 Jul 7;185(14):2559-2575.e28. doi: 10.1016/j.cell.2022.05.013. Epub 2022 Jun 9. Cell. 2022. PMID: 35688146 Free PMC article.
Integrator is a global promoter-proximal termination complex.
Wagner EJ, Tong L, Adelman K. Wagner EJ, et al. Among authors: adelman k. Mol Cell. 2023 Feb 2;83(3):416-427. doi: 10.1016/j.molcel.2022.11.012. Epub 2023 Jan 11. Mol Cell. 2023. PMID: 36634676 Free PMC article. Review.
Non-coding RNA: More uses for genomic junk.
Adelman K, Egan E. Adelman K, et al. Nature. 2017 Mar 8;543(7644):183-185. doi: 10.1038/543183a. Nature. 2017. PMID: 28277509 No abstract available.
RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells.
Santoriello C, Sporrij A, Yang S, Flynn RA, Henriques T, Dorjsuren B, Custo Greig E, McCall W, Stanhope ME, Fazio M, Superdock M, Lichtig A, Adatto I, Abraham BJ, Kalocsay M, Jurynec M, Zhou Y, Adelman K, Calo E, Zon LI. Santoriello C, et al. Among authors: adelman k. Nat Cell Biol. 2020 Apr;22(4):372-379. doi: 10.1038/s41556-020-0493-0. Epub 2020 Mar 30. Nat Cell Biol. 2020. PMID: 32231306 Free PMC article.
Intragenic Enhancers Attenuate Host Gene Expression.
Cinghu S, Yang P, Kosak JP, Conway AE, Kumar D, Oldfield AJ, Adelman K, Jothi R. Cinghu S, et al. Among authors: adelman k. Mol Cell. 2017 Oct 5;68(1):104-117.e6. doi: 10.1016/j.molcel.2017.09.010. Mol Cell. 2017. PMID: 28985501 Free PMC article.
101 results