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Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq.
Replogle JM, Saunders RA, Pogson AN, Hussmann JA, Lenail A, Guna A, Mascibroda L, Wagner EJ, Adelman K, Lithwick-Yanai G, Iremadze N, Oberstrass F, Lipson D, Bonnar JL, Jost M, Norman TM, Weissman JS. Replogle JM, et al. Among authors: lipson d. Cell. 2022 Jul 7;185(14):2559-2575.e28. doi: 10.1016/j.cell.2022.05.013. Epub 2022 Jun 9. Cell. 2022. PMID: 35688146 Free PMC article.
Mostly natural sequencing-by-synthesis for scRNA-seq using Ultima sequencing.
Simmons SK, Lithwick-Yanai G, Adiconis X, Oberstrass F, Iremadze N, Geiger-Schuller K, Thakore PI, Frangieh CJ, Barad O, Almogy G, Rozenblatt-Rosen O, Regev A, Lipson D, Levin JZ. Simmons SK, et al. Among authors: lipson d. Nat Biotechnol. 2023 Feb;41(2):204-211. doi: 10.1038/s41587-022-01452-6. Epub 2022 Sep 15. Nat Biotechnol. 2023. PMID: 36109685 Free PMC article.
Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting.
He J, Abdel-Wahab O, Nahas MK, Wang K, Rampal RK, Intlekofer AM, Patel J, Krivstov A, Frampton GM, Young LE, Zhong S, Bailey M, White JR, Roels S, Deffenbaugh J, Fichtenholtz A, Brennan T, Rosenzweig M, Pelak K, Knapp KM, Brennan KW, Donahue AL, Young G, Garcia L, Beckstrom ST, Zhao M, White E, Banning V, Buell J, Iwanik K, Ross JS, Morosini D, Younes A, Hanash AM, Paietta E, Roberts K, Mullighan C, Dogan A, Armstrong SA, Mughal T, Vergilio JA, Labrecque E, Erlich R, Vietz C, Yelensky R, Stephens PJ, Miller VA, van den Brink MR, Otto GA, Lipson D, Levine RL. He J, et al. Among authors: lipson d. Blood. 2016 Jun 16;127(24):3004-14. doi: 10.1182/blood-2015-08-664649. Epub 2016 Mar 10. Blood. 2016. PMID: 26966091 Free PMC article.
Global organization of replication time zones of the mouse genome.
Farkash-Amar S, Lipson D, Polten A, Goren A, Helmstetter C, Yakhini Z, Simon I. Farkash-Amar S, et al. Among authors: lipson d. Genome Res. 2008 Oct;18(10):1562-70. doi: 10.1101/gr.079566.108. Epub 2008 Jul 30. Genome Res. 2008. PMID: 18669478 Free PMC article.
Broad, Hybrid Capture-Based Next-Generation Sequencing Identifies Actionable Genomic Alterations in Lung Adenocarcinomas Otherwise Negative for Such Alterations by Other Genomic Testing Approaches.
Drilon A, Wang L, Arcila ME, Balasubramanian S, Greenbowe JR, Ross JS, Stephens P, Lipson D, Miller VA, Kris MG, Ladanyi M, Rizvi NA. Drilon A, et al. Among authors: lipson d. Clin Cancer Res. 2015 Aug 15;21(16):3631-9. doi: 10.1158/1078-0432.CCR-14-2683. Epub 2015 Jan 7. Clin Cancer Res. 2015. PMID: 25567908 Free PMC article.
Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing.
Frampton GM, Fichtenholtz A, Otto GA, Wang K, Downing SR, He J, Schnall-Levin M, White J, Sanford EM, An P, Sun J, Juhn F, Brennan K, Iwanik K, Maillet A, Buell J, White E, Zhao M, Balasubramanian S, Terzic S, Richards T, Banning V, Garcia L, Mahoney K, Zwirko Z, Donahue A, Beltran H, Mosquera JM, Rubin MA, Dogan S, Hedvat CV, Berger MF, Pusztai L, Lechner M, Boshoff C, Jarosz M, Vietz C, Parker A, Miller VA, Ross JS, Curran J, Cronin MT, Stephens PJ, Lipson D, Yelensky R. Frampton GM, et al. Among authors: lipson d. Nat Biotechnol. 2013 Nov;31(11):1023-31. doi: 10.1038/nbt.2696. Epub 2013 Oct 20. Nat Biotechnol. 2013. PMID: 24142049 Free PMC article.
Virtual terminator nucleotides for next-generation DNA sequencing.
Bowers J, Mitchell J, Beer E, Buzby PR, Causey M, Efcavitch JW, Jarosz M, Krzymanska-Olejnik E, Kung L, Lipson D, Lowman GM, Marappan S, McInerney P, Platt A, Roy A, Siddiqi SM, Steinmann K, Thompson JF. Bowers J, et al. Among authors: lipson d. Nat Methods. 2009 Aug;6(8):593-5. doi: 10.1038/nmeth.1354. Epub 2009 Jul 20. Nat Methods. 2009. PMID: 19620973 Free PMC article.
Comprehensive genomic profiling of relapsed and metastatic adenoid cystic carcinomas by next-generation sequencing reveals potential new routes to targeted therapies.
Ross JS, Wang K, Rand JV, Sheehan CE, Jennings TA, Al-Rohil RN, Otto GA, Curran JC, Palmer G, Downing SR, Yelensky R, Lipson D, Balasubramanian S, Garcia L, Mahoney K, Ali SM, Miller VA, Stephens PJ. Ross JS, et al. Among authors: lipson d. Am J Surg Pathol. 2014 Feb;38(2):235-8. doi: 10.1097/PAS.0000000000000102. Am J Surg Pathol. 2014. PMID: 24418857
353 results