Rüegg MA - Search Results

1

Novel roles of mTORC2 in regulation of insulin secretion by actin filament remodeling.

Blandino-Rosano M, Scheys JO, Werneck-de-Castro JP, Louzada RA, Almaça J, Leibowitz G, Rüegg MA, Hall MN, Bernal-Mizrachi E. Blandino-Rosano M, et al. Among authors: ruegg ma. Am J Physiol Endocrinol Metab. 2022 Aug 1;323(2):E133-E144. doi: 10.1152/ajpendo.00076.2022. Epub 2022 Jun 20. Am J Physiol Endocrinol Metab. 2022. PMID: 35723227 Free PMC article.

2

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.

Jacinto E, Loewith R, Schmidt A, Lin S, Rüegg MA, Hall A, Hall MN. Jacinto E, et al. Among authors: ruegg ma. Nat Cell Biol. 2004 Nov;6(11):1122-8. doi: 10.1038/ncb1183. Epub 2004 Oct 3. Nat Cell Biol. 2004. PMID: 15467718

3

Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration.

Polak P, Cybulski N, Feige JN, Auwerx J, Rüegg MA, Hall MN. Polak P, et al. Among authors: ruegg ma. Cell Metab. 2008 Nov;8(5):399-410. doi: 10.1016/j.cmet.2008.09.003. Cell Metab. 2008. PMID: 19046571 Free article.

4

Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy.

Bentzinger CF, Romanino K, Cloëtta D, Lin S, Mascarenhas JB, Oliveri F, Xia J, Casanova E, Costa CF, Brink M, Zorzato F, Hall MN, Rüegg MA. Bentzinger CF, et al. Among authors: ruegg ma. Cell Metab. 2008 Nov;8(5):411-24. doi: 10.1016/j.cmet.2008.10.002. Cell Metab. 2008. PMID: 19046572 Free article.

5

The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor- or rictor-independent manner.

Patursky-Polischuk I, Stolovich-Rain M, Hausner-Hanochi M, Kasir J, Cybulski N, Avruch J, Rüegg MA, Hall MN, Meyuhas O. Patursky-Polischuk I, et al. Among authors: ruegg ma. Mol Cell Biol. 2009 Feb;29(3):640-9. doi: 10.1128/MCB.00980-08. Epub 2008 Dec 1. Mol Cell Biol. 2009. PMID: 19047368 Free PMC article.

6

mTOR complex 2 in adipose tissue negatively controls whole-body growth.

Cybulski N, Polak P, Auwerx J, Rüegg MA, Hall MN. Cybulski N, et al. Among authors: ruegg ma. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9902-7. doi: 10.1073/pnas.0811321106. Epub 2009 Jun 3. Proc Natl Acad Sci U S A. 2009. PMID: 19497867 Free PMC article.

7

Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice.

Shende P, Plaisance I, Morandi C, Pellieux C, Berthonneche C, Zorzato F, Krishnan J, Lerch R, Hall MN, Rüegg MA, Pedrazzini T, Brink M. Shende P, et al. Among authors: ruegg ma. Circulation. 2011 Mar 15;123(10):1073-82. doi: 10.1161/CIRCULATIONAHA.110.977066. Epub 2011 Feb 28. Circulation. 2011. PMID: 21357822

8

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice.

Inoki K, Mori H, Wang J, Suzuki T, Hong S, Yoshida S, Blattner SM, Ikenoue T, Rüegg MA, Hall MN, Kwiatkowski DJ, Rastaldi MP, Huber TB, Kretzler M, Holzman LB, Wiggins RC, Guan KL. Inoki K, et al. Among authors: ruegg ma. J Clin Invest. 2011 Jun;121(6):2181-96. doi: 10.1172/JCI44771. Epub 2011 May 23. J Clin Invest. 2011. PMID: 21606597 Free PMC article.

9

Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c.

Hagiwara A, Cornu M, Cybulski N, Polak P, Betz C, Trapani F, Terracciano L, Heim MH, Rüegg MA, Hall MN. Hagiwara A, et al. Among authors: ruegg ma. Cell Metab. 2012 May 2;15(5):725-38. doi: 10.1016/j.cmet.2012.03.015. Epub 2012 Apr 19. Cell Metab. 2012. PMID: 22521878 Free article.

10

Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy.

Bentzinger CF, Lin S, Romanino K, Castets P, Guridi M, Summermatter S, Handschin C, Tintignac LA, Hall MN, Rüegg MA. Bentzinger CF, et al. Among authors: ruegg ma. Skelet Muscle. 2013 Mar 6;3(1):6. doi: 10.1186/2044-5040-3-6. Skelet Muscle. 2013. PMID: 23497627 Free PMC article.

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