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Programmable antivirals targeting critical conserved viral RNA secondary structures from influenza A virus and SARS-CoV-2.
Hagey RJ, Elazar M, Pham EA, Tian S, Ben-Avi L, Bernardin-Souibgui C, Yee MF, Moreira FR, Rabinovitch MV, Meganck RM, Fram B, Beck A, Gibson SA, Lam G, Devera J, Kladwang W, Nguyen K, Xiong A, Schaffert S, Avisar T, Liu P, Rustagi A, Fichtenbaum CJ, Pang PS, Khatri P, Tseng CT, Taubenberger JK, Blish CA, Hurst BL, Sheahan TP, Das R, Glenn JS. Hagey RJ, et al. Among authors: pham ea. Nat Med. 2022 Sep;28(9):1944-1955. doi: 10.1038/s41591-022-01908-x. Epub 2022 Aug 18. Nat Med. 2022. PMID: 35982307 Free PMC article.
Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome.
Zhang K, Zheludev IN, Hagey RJ, Haslecker R, Hou YJ, Kretsch R, Pintilie GD, Rangan R, Kladwang W, Li S, Wu MT, Pham EA, Bernardin-Souibgui C, Baric RS, Sheahan TP, D'Souza V, Glenn JS, Chiu W, Das R. Zhang K, et al. Among authors: pham ea. Nat Struct Mol Biol. 2021 Sep;28(9):747-754. doi: 10.1038/s41594-021-00653-y. Epub 2021 Aug 23. Nat Struct Mol Biol. 2021. PMID: 34426697 Free PMC article.
Future Therapy for Hepatitis B Virus: Role of Immunomodulators.
Pham EA, Perumpail RB, Fram BJ, Glenn JS, Ahmed A, Gish RG. Pham EA, et al. Curr Hepatol Rep. 2016;15(4):237-244. doi: 10.1007/s11901-016-0315-9. Epub 2016 Nov 10. Curr Hepatol Rep. 2016. PMID: 27917363 Free PMC article. Review.
Cryo-electron Microscopy and Exploratory Antisense Targeting of the 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome.
Zhang K, Zheludev IN, Hagey RJ, Wu MT, Haslecker R, Hou YJ, Kretsch R, Pintilie GD, Rangan R, Kladwang W, Li S, Pham EA, Bernardin-Souibgui C, Baric RS, Sheahan TP, D Souza V, Glenn JS, Chiu W, Das R. Zhang K, et al. Among authors: pham ea. bioRxiv [Preprint]. 2020 Jul 20:2020.07.18.209270. doi: 10.1101/2020.07.18.209270. bioRxiv. 2020. PMID: 32743589 Free PMC article. Updated. Preprint.
Structural map of a microRNA-122: hepatitis C virus complex.
Pang PS, Pham EA, Elazar M, Patel SG, Eckart MR, Glenn JS. Pang PS, et al. Among authors: pham ea. J Virol. 2012 Jan;86(2):1250-4. doi: 10.1128/JVI.06367-11. Epub 2011 Nov 9. J Virol. 2012. PMID: 22072754 Free PMC article.
Signatures of immune dysfunction in HIV and HCV infection share features with chronic inflammation in aging and persist after viral reduction or elimination.
Lopez Angel CJ, Pham EA, Du H, Vallania F, Fram BJ, Perez K, Nguyen T, Rosenberg-Hasson Y, Ahmed A, Dekker CL, Grant PM, Khatri P, Maecker HT, Glenn JS, Davis MM, Furman D. Lopez Angel CJ, et al. Among authors: pham ea. Proc Natl Acad Sci U S A. 2021 Apr 6;118(14):e2022928118. doi: 10.1073/pnas.2022928118. Proc Natl Acad Sci U S A. 2021. PMID: 33811141 Free PMC article.
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