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Fructose induced KHK-C can increase ER stress independent of its effect on lipogenesis to drive liver disease in diet-induced and genetic models of NAFLD.
Park SH, Helsley RN, Fadhul T, Willoughby JLS, Noetzli L, Tu HC, Solheim MH, Fujisaka S, Pan H, Dreyfuss JM, Bons J, Rose J, King CD, Schilling B, Lusis AJ, Pan C, Gupta M, Kulkarni RN, Fitzgerald K, Kern PA, Divanovic S, Kahn CR, Softic S. Park SH, et al. Among authors: dreyfuss jm. Metabolism. 2023 Aug;145:155591. doi: 10.1016/j.metabol.2023.155591. Epub 2023 May 23. Metabolism. 2023. PMID: 37230214
Antibiotic effects on gut microbiota and metabolism are host dependent.
Fujisaka S, Ussar S, Clish C, Devkota S, Dreyfuss JM, Sakaguchi M, Soto M, Konishi M, Softic S, Altindis E, Li N, Gerber G, Bry L, Kahn CR. Fujisaka S, et al. Among authors: dreyfuss jm. J Clin Invest. 2016 Dec 1;126(12):4430-4443. doi: 10.1172/JCI86674. Epub 2016 Oct 24. J Clin Invest. 2016. PMID: 27775551 Free PMC article.
Adipose-derived circulating miRNAs regulate gene expression in other tissues.
Thomou T, Mori MA, Dreyfuss JM, Konishi M, Sakaguchi M, Wolfrum C, Rao TN, Winnay JN, Garcia-Martin R, Grinspoon SK, Gorden P, Kahn CR. Thomou T, et al. Among authors: dreyfuss jm. Nature. 2017 Feb 23;542(7642):450-455. doi: 10.1038/nature21365. Epub 2017 Feb 15. Nature. 2017. PMID: 28199304 Free PMC article.
YAP suppresses gluconeogenic gene expression through PGC1α.
Hu Y, Shin DJ, Pan H, Lin Z, Dreyfuss JM, Camargo FD, Miao J, Biddinger SB. Hu Y, et al. Among authors: dreyfuss jm. Hepatology. 2017 Dec;66(6):2029-2041. doi: 10.1002/hep.29373. Epub 2017 Oct 30. Hepatology. 2017. PMID: 28714135 Free PMC article.
Metabolic Effects of Betaine: A Randomized Clinical Trial of Betaine Supplementation in Prediabetes.
Grizales AM, Patti ME, Lin AP, Beckman JA, Sahni VA, Cloutier E, Fowler KM, Dreyfuss JM, Pan H, Kozuka C, Lee A, Basu R, Pober DM, Gerszten RE, Goldfine AB. Grizales AM, et al. Among authors: dreyfuss jm. J Clin Endocrinol Metab. 2018 Aug 1;103(8):3038-3049. doi: 10.1210/jc.2018-00507. J Clin Endocrinol Metab. 2018. PMID: 29860335 Free PMC article. Clinical Trial.
67 results