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Natural history of β-cell adaptation and failure in type 2 diabetes.
Alejandro EU, Gregg B, Blandino-Rosano M, Cras-Méneur C, Bernal-Mizrachi E. Alejandro EU, et al. Mol Aspects Med. 2015 Apr;42:19-41. doi: 10.1016/j.mam.2014.12.002. Epub 2014 Dec 24. Mol Aspects Med. 2015. PMID: 25542976 Free PMC article. Review.
Loss of mTORC1 signalling impairs β-cell homeostasis and insulin processing.
Blandino-Rosano M, Barbaresso R, Jimenez-Palomares M, Bozadjieva N, Werneck-de-Castro JP, Hatanaka M, Mirmira RG, Sonenberg N, Liu M, Rüegg MA, Hall MN, Bernal-Mizrachi E. Blandino-Rosano M, et al. Nat Commun. 2017 Jul 12;8:16014. doi: 10.1038/ncomms16014. Nat Commun. 2017. PMID: 28699639 Free PMC article.
Loss of mTORC1 signaling alters pancreatic α cell mass and impairs glucagon secretion.
Bozadjieva N, Blandino-Rosano M, Chase J, Dai XQ, Cummings K, Gimeno J, Dean D, Powers AC, Gittes GK, Rüegg MA, Hall MN, MacDonald PE, Bernal-Mizrachi E. Bozadjieva N, et al. J Clin Invest. 2017 Dec 1;127(12):4379-4393. doi: 10.1172/JCI90004. Epub 2017 Nov 6. J Clin Invest. 2017. PMID: 29106387 Free PMC article.
Nutrient Sensor mTORC1 Regulates Insulin Secretion by Modulating β-Cell Autophagy.
Israeli T, Riahi Y, Garzon P, Louzada RA, Werneck-de-Castro JP, Blandino-Rosano M, Yeroslaviz-Stolper R, Kadosh L, Tornovsky-Babeay S, Hacker G, Israeli N, Agmon O, Tirosh B, Cerasi E, Bernal-Mizrachi E, Leibowitz G. Israeli T, et al. Among authors: blandino rosano m. Diabetes. 2022 Mar 1;71(3):453-469. doi: 10.2337/db21-0281. Diabetes. 2022. PMID: 34862201 Free PMC article.
Novel roles of mTORC2 in regulation of insulin secretion by actin filament remodeling.
Blandino-Rosano M, Scheys JO, Werneck-de-Castro JP, Louzada RA, Almaça J, Leibowitz G, Rüegg MA, Hall MN, Bernal-Mizrachi E. Blandino-Rosano M, et al. Am J Physiol Endocrinol Metab. 2022 Aug 1;323(2):E133-E144. doi: 10.1152/ajpendo.00076.2022. Epub 2022 Jun 20. Am J Physiol Endocrinol Metab. 2022. PMID: 35723227 Free PMC article.
GHRH agonist MR-409 protects β-cells from streptozotocin-induced diabetes.
Louzada RA, Blandino-Rosano M, Flores S, Lubaczeuski C, Cui T, Sha W, Cai R, Schally AV, Bernal-Mizrachi E. Louzada RA, et al. Among authors: blandino rosano m. Proc Natl Acad Sci U S A. 2023 Jun 20;120(25):e2209810120. doi: 10.1073/pnas.2209810120. Epub 2023 Jun 12. Proc Natl Acad Sci U S A. 2023. PMID: 37307472 Free PMC article.
Glucose stimulates microRNA-199 expression in murine pancreatic β-cells.
Werneck-de-Castro JP, Blandino-Rosano M, Hilfiker-Kleiner D, Bernal-Mizrachi E. Werneck-de-Castro JP, et al. Among authors: blandino rosano m. J Biol Chem. 2020 Jan 31;295(5):1261-1270. doi: 10.1074/jbc.RA119.010356. Epub 2019 Dec 27. J Biol Chem. 2020. PMID: 31882540 Free PMC article.
26 results