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Redox regulation of m6A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes.
F De Jesus D, Zhang Z, Brown NK, Li X, Xiao L, Hu J, Gaffrey MJ, Fogarty G, Kahraman S, Wei J, Basile G, Rana TM, Mathews C, Powers AC, Parent AV, Atkinson MA, Dhe-Paganon S, Eizirik DL, Qian WJ, He C, Kulkarni RN. F De Jesus D, et al. Among authors: eizirik dl. Nat Cell Biol. 2024 Mar;26(3):421-437. doi: 10.1038/s41556-024-01368-0. Epub 2024 Feb 26. Nat Cell Biol. 2024. PMID: 38409327 Free PMC article.
Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention.
Nakayasu ES, Syed F, Tersey SA, Gritsenko MA, Mitchell HD, Chan CY, Dirice E, Turatsinze JV, Cui Y, Kulkarni RN, Eizirik DL, Qian WJ, Webb-Robertson BM, Evans-Molina C, Mirmira RG, Metz TO. Nakayasu ES, et al. Among authors: eizirik dl. Cell Metab. 2020 Feb 4;31(2):363-374.e6. doi: 10.1016/j.cmet.2019.12.005. Epub 2020 Jan 9. Cell Metab. 2020. PMID: 31928885 Free PMC article.
SUMO wrestling with type 1 diabetes.
Li M, Guo D, Isales CM, Eizirik DL, Atkinson M, She JX, Wang CY. Li M, et al. Among authors: eizirik dl. J Mol Med (Berl). 2005 Jul;83(7):504-13. doi: 10.1007/s00109-005-0645-5. Epub 2005 Apr 2. J Mol Med (Berl). 2005. PMID: 15806321 Review.
Viral infections in type 1 diabetes mellitus--why the β cells?
Op de Beeck A, Eizirik DL. Op de Beeck A, et al. Among authors: eizirik dl. Nat Rev Endocrinol. 2016 May;12(5):263-273. doi: 10.1038/nrendo.2016.30. Epub 2016 Mar 29. Nat Rev Endocrinol. 2016. PMID: 27020257 Free PMC article. Review.
An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells.
Colli ML, Ramos-Rodríguez M, Nakayasu ES, Alvelos MI, Lopes M, Hill JLE, Turatsinze JV, Coomans de Brachène A, Russell MA, Raurell-Vila H, Castela A, Juan-Mateu J, Webb-Robertson BM, Krogvold L, Dahl-Jorgensen K, Marselli L, Marchetti P, Richardson SJ, Morgan NG, Metz TO, Pasquali L, Eizirik DL. Colli ML, et al. Among authors: eizirik dl. Nat Commun. 2020 May 22;11(1):2584. doi: 10.1038/s41467-020-16327-0. Nat Commun. 2020. PMID: 32444635 Free PMC article.
410 results