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Reciprocal crosstalk between Th17 and mesothelial cells promotes metastasis-associated adhesion of ovarian cancer cells.
Neuhaus F, Lieber S, Shinkevich V, Steitz AM, Raifer H, Roth K, Finkernagel F, Worzfeld T, Burchert A, Keber C, Nist A, Stiewe T, Reinartz S, Beutgen VM, Graumann J, Pauck K, Garn H, Gaida M, Müller R, Huber M. Neuhaus F, et al. Among authors: raifer h. Clin Transl Med. 2024 Apr;14(4):e1604. doi: 10.1002/ctm2.1604. Clin Transl Med. 2024. PMID: 38566518 Free PMC article.
Prognosis of ovarian cancer is associated with effector memory CD8+ T cell accumulation in ascites, CXCL9 levels and activation-triggered signal transduction in T cells.
Lieber S, Reinartz S, Raifer H, Finkernagel F, Dreyer T, Bronger H, Jansen JM, Wagner U, Worzfeld T, Müller R, Huber M. Lieber S, et al. Among authors: raifer h. Oncoimmunology. 2018 Mar 15;7(5):e1424672. doi: 10.1080/2162402X.2018.1424672. eCollection 2018. Oncoimmunology. 2018. PMID: 29721385 Free PMC article.
Lactate induces metabolic and epigenetic reprogramming of pro-inflammatory Th17 cells.
Lopez Krol A, Nehring HP, Krause FF, Wempe A, Raifer H, Nist A, Stiewe T, Bertrams W, Schmeck B, Luu M, Leister H, Chung HR, Bauer UM, Adhikary T, Visekruna A. Lopez Krol A, et al. Among authors: raifer h. EMBO Rep. 2022 Dec 6;23(12):e54685. doi: 10.15252/embr.202254685. Epub 2022 Oct 10. EMBO Rep. 2022. PMID: 36215678 Free PMC article.
IL-17A-producing CD8+ T cells promote PDAC via induction of inflammatory cancer-associated fibroblasts.
Picard FSR, Lutz V, Brichkina A, Neuhaus F, Ruckenbrod T, Hupfer A, Raifer H, Klein M, Bopp T, Pfefferle PI, Savai R, Prinz I, Waisman A, Moos S, Chang HD, Heinrich S, Bartsch DK, Buchholz M, Singh S, Tu M, Klein L, Bauer C, Liefke R, Burchert A, Chung HR, Mayer P, Gress TM, Lauth M, Gaida M, Huber M. Picard FSR, et al. Among authors: raifer h. Gut. 2023 Aug;72(8):1510-1522. doi: 10.1136/gutjnl-2022-327855. Epub 2023 Feb 9. Gut. 2023. PMID: 36759154 Free PMC article.
The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes.
Luu M, Pautz S, Kohl V, Singh R, Romero R, Lucas S, Hofmann J, Raifer H, Vachharajani N, Carrascosa LC, Lamp B, Nist A, Stiewe T, Shaul Y, Adhikary T, Zaiss MM, Lauth M, Steinhoff U, Visekruna A. Luu M, et al. Among authors: raifer h. Nat Commun. 2019 Feb 15;10(1):760. doi: 10.1038/s41467-019-08711-2. Nat Commun. 2019. PMID: 30770822 Free PMC article.
IL18 Receptor Signaling Regulates Tumor-Reactive CD8+ T-cell Exhaustion via Activation of the IL2/STAT5/mTOR Pathway in a Pancreatic Cancer Model.
Lutz V, Hellmund VM, Picard FSR, Raifer H, Ruckenbrod T, Klein M, Bopp T, Savai R, Duewell P, Keber CU, Weigert A, Chung HR, Buchholz M, Menke A, Gress TM, Huber M, Bauer C. Lutz V, et al. Among authors: raifer h. Cancer Immunol Res. 2023 Apr 3;11(4):421-434. doi: 10.1158/2326-6066.CIR-22-0398. Cancer Immunol Res. 2023. PMID: 36758176
Tc9 cells, a new subset of CD8(+) T cells, support Th2-mediated airway inflammation.
Visekruna A, Ritter J, Scholz T, Campos L, Guralnik A, Poncette L, Raifer H, Hagner S, Garn H, Staudt V, Bopp T, Reuter S, Taube C, Loser K, Huber M. Visekruna A, et al. Among authors: raifer h. Eur J Immunol. 2013 Mar;43(3):606-18. doi: 10.1002/eji.201242825. Epub 2013 Jan 31. Eur J Immunol. 2013. PMID: 23254356 Free article.
Microenvironmental Th9 and Th17 lymphocytes induce metastatic spreading in lung cancer.
Salazar Y, Zheng X, Brunn D, Raifer H, Picard F, Zhang Y, Winter H, Guenther S, Weigert A, Weigmann B, Dumoutier L, Renauld JC, Waisman A, Schmall A, Tufman A, Fink L, Brüne B, Bopp T, Grimminger F, Seeger W, Pullamsetti SS, Huber M, Savai R. Salazar Y, et al. Among authors: raifer h. J Clin Invest. 2020 Jul 1;130(7):3560-3575. doi: 10.1172/JCI124037. J Clin Invest. 2020. PMID: 32229721 Free PMC article.
43 results