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Molecular modeling and site-directed mutagenesis of an anti-phosphotyrosine antibody predicts the combining site and allows the detection of higher affinity interactions.
Protein Eng. 1993 Aug;6(6):661-8. doi: 10.1093/protein/6.6.661.
Protein Eng. 1993.
PMID: 7694275
Heavy and light chain variable region sequences and antibody properties of anti-phosphotyrosine antibodies reveal both common and distinct features.
Ruff-Jamison S, Campos-González R, Glenney JR Jr.
Ruff-Jamison S, et al.
J Biol Chem. 1991 Apr 5;266(10):6607-13.
J Biol Chem. 1991.
PMID: 1706720
Free article.
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Requirement for both H and L chain V regions, VH and VK joining amino acids, and the unique H chain D region for the high affinity binding of an anti-phosphotyrosine antibody.
Ruff-Jamison S, Glenney JR Jr.
Ruff-Jamison S, et al.
J Immunol. 1993 Apr 15;150(8 Pt 1):3389-96.
J Immunol. 1993.
PMID: 7682239
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Epidermal growth factor induces the tyrosine phosphorylation and nuclear translocation of Stat 5 in mouse liver.
Ruff-Jamison S, Chen K, Cohen S.
Ruff-Jamison S, et al.
Proc Natl Acad Sci U S A. 1995 May 9;92(10):4215-8. doi: 10.1073/pnas.92.10.4215.
Proc Natl Acad Sci U S A. 1995.
PMID: 7538664
Free PMC article.
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Epidermal growth factor and lipopolysaccharide activate Stat3 transcription factor in mouse liver.
Ruff-Jamison S, Zhong Z, Wen Z, Chen K, Darnell JE Jr, Cohen S.
Ruff-Jamison S, et al.
J Biol Chem. 1994 Sep 2;269(35):21933-5.
J Biol Chem. 1994.
PMID: 8071311
Free article.
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Induction by EGF and interferon-gamma of tyrosine phosphorylated DNA binding proteins in mouse liver nuclei.
Ruff-Jamison S, Chen K, Cohen S.
Ruff-Jamison S, et al.
Science. 1993 Sep 24;261(5129):1733-6. doi: 10.1126/science.8378774.
Science. 1993.
PMID: 8378774
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Epidermal growth factor stimulates the tyrosine phosphorylation of SHC in the mouse.
Ruff-Jamison S, McGlade J, Pawson T, Chen K, Cohen S.
Ruff-Jamison S, et al.
J Biol Chem. 1993 Apr 15;268(11):7610-2.
J Biol Chem. 1993.
PMID: 7681824
Free article.
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