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Year Number of Results
2017 3
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2020 4
2021 2
2022 1
2023 2
2024 1

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Page 1
Biosynthesis of prostaglandin 15dPGJ2 -glutathione and 15dPGJ2-cysteine conjugates in macrophages and mast cells via MGST3.
Steinmetz-Späh J, Liu J, Singh R, Ekoff M, Boddul S, Tang X, Bergqvist F, Idborg H, Heitel P, Rönnberg E, Merk D, Wermeling F, Haeggström JZ, Nilsson G, Steinhilber D, Larsson K, Korotkova M, Jakobsson PJ. Steinmetz-Späh J, et al. Among authors: heitel p. J Lipid Res. 2022 Dec;63(12):100310. doi: 10.1016/j.jlr.2022.100310. Epub 2022 Nov 9. J Lipid Res. 2022. PMID: 36370807 Free PMC article.
The Transcriptional Repressor Orphan Nuclear Receptor TLX Is Responsive to Xanthines.
Faudone G, Kilu W, Ni X, Chaikuad A, Sreeramulu S, Heitel P, Schwalbe H, Knapp S, Schubert-Zsilavecz M, Heering J, Merk D. Faudone G, et al. Among authors: heitel p. ACS Pharmacol Transl Sci. 2021 Nov 23;4(6):1794-1807. doi: 10.1021/acsptsci.1c00195. eCollection 2021 Dec 10. ACS Pharmacol Transl Sci. 2021. PMID: 34927011 Free PMC article.
Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain.
Brand M, Clayton J, Moroglu M, Schiedel M, Picaud S, Bluck JP, Skwarska A, Bolland H, Chan AKN, Laurin CMC, Scorah AR, See L, Rooney TPC, Andrews KH, Fedorov O, Perell G, Kalra P, Vinh KB, Cortopassi WA, Heitel P, Christensen KE, Cooper RI, Paton RS, Pomerantz WCK, Biggin PC, Hammond EM, Filippakopoulos P, Conway SJ. Brand M, et al. Among authors: heitel p. J Med Chem. 2021 Jul 22;64(14):10102-10123. doi: 10.1021/acs.jmedchem.1c00348. Epub 2021 Jul 13. J Med Chem. 2021. PMID: 34255515 Free PMC article.
Design and Structural Optimization of Dual FXR/PPARδ Activators.
Schierle S, Neumann S, Heitel P, Willems S, Kaiser A, Pollinger J, Merk D. Schierle S, et al. Among authors: heitel p. J Med Chem. 2020 Aug 13;63(15):8369-8379. doi: 10.1021/acs.jmedchem.0c00618. Epub 2020 Jul 20. J Med Chem. 2020. PMID: 32687365
l-Thyroxin and the Nonclassical Thyroid Hormone TETRAC Are Potent Activators of PPARγ.
Gellrich L, Heitel P, Heering J, Kilu W, Pollinger J, Goebel T, Kahnt A, Arifi S, Pogoda W, Paulke A, Steinhilber D, Proschak E, Wurglics M, Schubert-Zsilavecz M, Chaikuad A, Knapp S, Bischoff I, Fürst R, Merk D. Gellrich L, et al. Among authors: heitel p. J Med Chem. 2020 Jul 9;63(13):6727-6740. doi: 10.1021/acs.jmedchem.9b02150. Epub 2020 Jun 4. J Med Chem. 2020. PMID: 32356658
Dual Farnesoid X Receptor/Soluble Epoxide Hydrolase Modulators Derived from Zafirlukast.
Schierle S, Helmstädter M, Schmidt J, Hartmann M, Horz M, Kaiser A, Weizel L, Heitel P, Proschak A, Hernandez-Olmos V, Proschak E, Merk D. Schierle S, et al. Among authors: heitel p. ChemMedChem. 2020 Jan 7;15(1):50-67. doi: 10.1002/cmdc.201900576. Epub 2019 Nov 19. ChemMedChem. 2020. PMID: 31670489 Free PMC article.
17 results