Bar-Peled L - Search Results

1

Bar-Peled L, Sabatini DM. Bar-Peled L, et al. Trends Cell Biol. 2014 Jul;24(7):400-6. doi: 10.1016/j.tcb.2014.03.003. Epub 2014 Mar 31. Trends Cell Biol. 2014. PMID: 24698685 Free PMC article. Review.

2

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.

Sancak Y, Peterson TR, Shaul YD, Lindquist RA, Thoreen CC, Bar-Peled L, Sabatini DM. Sancak Y, et al. Science. 2008 Jun 13;320(5882):1496-501. doi: 10.1126/science.1157535. Epub 2008 May 22. Science. 2008. PMID: 18497260 Free PMC article.

3

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.

Sancak Y, Bar-Peled L, Zoncu R, Markhard AL, Nada S, Sabatini DM. Sancak Y, et al. Cell. 2010 Apr 16;141(2):290-303. doi: 10.1016/j.cell.2010.02.024. Epub 2010 Apr 8. Cell. 2010. PMID: 20381137 Free PMC article.

4

mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase.

Zoncu R, Bar-Peled L, Efeyan A, Wang S, Sancak Y, Sabatini DM. Zoncu R, et al. Science. 2011 Nov 4;334(6056):678-83. doi: 10.1126/science.1207056. Science. 2011. PMID: 22053050 Free PMC article.

5

Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1.

Bar-Peled L, Schweitzer LD, Zoncu R, Sabatini DM. Bar-Peled L, et al. Cell. 2012 Sep 14;150(6):1196-208. doi: 10.1016/j.cell.2012.07.032. Cell. 2012. PMID: 22980980 Free PMC article.

6

SnapShot: mTORC1 signaling at the lysosomal surface.

Bar-Peled L, Sabatini DM. Bar-Peled L, et al. Cell. 2012 Dec 7;151(6):1390-1390.e1. doi: 10.1016/j.cell.2012.11.038. Cell. 2012. PMID: 23217718 Free article. No abstract available.

7

A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1.

Bar-Peled L, Chantranupong L, Cherniack AD, Chen WW, Ottina KA, Grabiner BC, Spear ED, Carter SL, Meyerson M, Sabatini DM. Bar-Peled L, et al. Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. Science. 2013. PMID: 23723238 Free PMC article.

8

The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1.

Tsun ZY, Bar-Peled L, Chantranupong L, Zoncu R, Wang T, Kim C, Spooner E, Sabatini DM. Tsun ZY, et al. Mol Cell. 2013 Nov 21;52(4):495-505. doi: 10.1016/j.molcel.2013.09.016. Epub 2013 Oct 3. Mol Cell. 2013. PMID: 24095279 Free PMC article.

9

The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1.

Chantranupong L, Wolfson RL, Orozco JM, Saxton RA, Scaria SM, Bar-Peled L, Spooner E, Isasa M, Gygi SP, Sabatini DM. Chantranupong L, et al. Cell Rep. 2014 Oct 9;9(1):1-8. doi: 10.1016/j.celrep.2014.09.014. Epub 2014 Sep 25. Cell Rep. 2014. PMID: 25263562 Free PMC article.

10

Science & SciLifeLab Prize Essay. Size does matter.

Bar-Peled L. Bar-Peled L. Science. 2014 Dec 5;346(6214):1191-2. doi: 10.1126/science.aaa1808. Science. 2014. PMID: 25477447 No abstract available.

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