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mTORC1 signaling and regulation of pancreatic β-cell mass.
Blandino-Rosano M, Chen AY, Scheys JO, Alejandro EU, Gould AP, Taranukha T, Elghazi L, Cras-Méneur C, Bernal-Mizrachi E. Blandino-Rosano M, et al. Cell Cycle. 2012 May 15;11(10):1892-902. doi: 10.4161/cc.20036. Epub 2012 May 15. Cell Cycle. 2012. PMID: 22544327 Free PMC article. Review.
Natural history of β-cell adaptation and failure in type 2 diabetes.
Alejandro EU, Gregg B, Blandino-Rosano M, Cras-Méneur C, Bernal-Mizrachi E. Alejandro EU, et al. Mol Aspects Med. 2015 Apr;42:19-41. doi: 10.1016/j.mam.2014.12.002. Epub 2014 Dec 24. Mol Aspects Med. 2015. PMID: 25542976 Free PMC article. Review.
4E-BP2/SH2B1/IRS2 Are Part of a Novel Feedback Loop That Controls β-Cell Mass.
Blandino-Rosano M, Scheys JO, Jimenez-Palomares M, Barbaresso R, Bender AS, Yanagiya A, Liu M, Rui L, Sonenberg N, Bernal-Mizrachi E. Blandino-Rosano M, et al. Diabetes. 2016 Aug;65(8):2235-48. doi: 10.2337/db15-1443. Epub 2016 May 23. Diabetes. 2016. PMID: 27217487 Free PMC article.
Loss of mTORC1 signalling impairs β-cell homeostasis and insulin processing.
Blandino-Rosano M, Barbaresso R, Jimenez-Palomares M, Bozadjieva N, Werneck-de-Castro JP, Hatanaka M, Mirmira RG, Sonenberg N, Liu M, Rüegg MA, Hall MN, Bernal-Mizrachi E. Blandino-Rosano M, et al. Nat Commun. 2017 Jul 12;8:16014. doi: 10.1038/ncomms16014. Nat Commun. 2017. PMID: 28699639 Free PMC article.
26 results