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TRPV3 in Drug Development.
Broad LM, Mogg AJ, Eberle E, Tolley M, Li DL, Knopp KL. Broad LM, et al. Among authors: eberle e. Pharmaceuticals (Basel). 2016 Sep 9;9(3):55. doi: 10.3390/ph9030055. Pharmaceuticals (Basel). 2016. PMID: 27618069 Free PMC article. Review.
LY2456302 is a novel, potent, orally-bioavailable small molecule kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders.
Rorick-Kehn LM, Witkin JM, Statnick MA, Eberle EL, McKinzie JH, Kahl SD, Forster BM, Wong CJ, Li X, Crile RS, Shaw DB, Sahr AE, Adams BL, Quimby SJ, Diaz N, Jimenez A, Pedregal C, Mitch CH, Knopp KL, Anderson WH, Cramer JW, McKinzie DL. Rorick-Kehn LM, et al. Among authors: eberle el. Neuropharmacology. 2014 Feb;77:131-44. doi: 10.1016/j.neuropharm.2013.09.021. Epub 2013 Sep 23. Neuropharmacology. 2014. PMID: 24071566
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