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Cross-talk between B cells, microglia and macrophages, and implications to central nervous system compartmentalized inflammation and progressive multiple sclerosis.
Touil H, Li R, Zuroff L, Moore CS, Healy L, Cignarella F, Piccio L, Ludwin S, Prat A, Gommerman J, Bennett FC, Jacobs D, Benjamins JA, Lisak RP, Antel JP, Bar-Or A. Touil H, et al. Among authors: jacobs d. EBioMedicine. 2023 Oct;96:104789. doi: 10.1016/j.ebiom.2023.104789. Epub 2023 Sep 11. EBioMedicine. 2023. PMID: 37703640 Free PMC article.
Cataclysmically disseminating neurologic presentation in an immunosuppressed lupus patient: From the National Multiple Sclerosis Society Case Conference Proceedings.
Perrone CM, Lisak RP, Meltzer EI, Sguigna P, Tizazu E, Jacobs D, Melamed E, Lucas A, Freeman L, Pardo G, Goodman A, Fox EJ, Costello K, Parsons MS, Zamvil SS, Frohman EM, Frohman TC. Perrone CM, et al. Among authors: jacobs d. Neurol Neuroimmunol Neuroinflamm. 2019 Jun 13;6(4):e582. doi: 10.1212/NXI.0000000000000582. eCollection 2019 Jul. Neurol Neuroimmunol Neuroinflamm. 2019. PMID: 31355318 Free PMC article. No abstract available.
Cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy.
Apostolidis SA, Kakara M, Painter MM, Goel RR, Mathew D, Lenzi K, Rezk A, Patterson KR, Espinoza DA, Kadri JC, Markowitz DM, E Markowitz C, Mexhitaj I, Jacobs D, Babb A, Betts MR, Prak ETL, Weiskopf D, Grifoni A, Lundgreen KA, Gouma S, Sette A, Bates P, Hensley SE, Greenplate AR, Wherry EJ, Li R, Bar-Or A. Apostolidis SA, et al. Among authors: jacobs d. Nat Med. 2021 Nov;27(11):1990-2001. doi: 10.1038/s41591-021-01507-2. Epub 2021 Sep 14. Nat Med. 2021. PMID: 34522051 Free PMC article.
Immune aging in multiple sclerosis is characterized by abnormal CD4 T cell activation and increased frequencies of cytotoxic CD4 T cells with advancing age.
Zuroff L, Rezk A, Shinoda K, Espinoza DA, Elyahu Y, Zhang B, Chen AA, Shinohara RT, Jacobs D, Alcalay RN, Tropea TF, Chen-Plotkin A, Monsonego A, Li R, Bar-Or A. Zuroff L, et al. Among authors: jacobs d. EBioMedicine. 2022 Aug;82:104179. doi: 10.1016/j.ebiom.2022.104179. Epub 2022 Jul 19. EBioMedicine. 2022. PMID: 35868128 Free PMC article.
Differential effects of anti-CD20 therapy on CD4 and CD8 T cells and implication of CD20-expressing CD8 T cells in MS disease activity.
Shinoda K, Li R, Rezk A, Mexhitaj I, Patterson KR, Kakara M, Zuroff L, Bennett JL, von Büdingen HC, Carruthers R, Edwards KR, Fallis R, Giacomini PS, Greenberg BM, Hafler DA, Ionete C, Kaunzner UW, Lock CB, Longbrake EE, Pardo G, Piehl F, Weber MS, Ziemssen T, Jacobs D, Gelfand JM, Cross AH, Cameron B, Musch B, Winger RC, Jia X, Harp CT, Herman A, Bar-Or A. Shinoda K, et al. Among authors: jacobs d. Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2207291120. doi: 10.1073/pnas.2207291120. Epub 2023 Jan 12. Proc Natl Acad Sci U S A. 2023. PMID: 36634138 Free PMC article.
Severe Neuroinvasive West Nile Virus in Association With Anti-CD20 Monotherapy for Multiple Sclerosis.
Thebault S, Gandelman S, Lane C, Kim EJ, Pileggi C, Zuroff L, Yamashita LD, Schindler MK, Chiu C, Wilson MR, Berger JR, Markowitz C, Bar-Or A, Fuller R, Brandstadter R, Pruitt AA, Jacobs DA. Thebault S, et al. Among authors: jacobs da. Neurol Neuroimmunol Neuroinflamm. 2023 Aug 10;10(5):e200154. doi: 10.1212/NXI.0000000000200154. Print 2023 Sep. Neurol Neuroimmunol Neuroinflamm. 2023. PMID: 37562975 Free PMC article.
The treatment of multiple sclerosis with inosine.
Markowitz CE, Spitsin S, Zimmerman V, Jacobs D, Udupa JK, Hooper DC, Koprowski H. Markowitz CE, et al. Among authors: jacobs d. J Altern Complement Med. 2009 Jun;15(6):619-25. doi: 10.1089/acm.2008.0513. J Altern Complement Med. 2009. PMID: 19425822 Free PMC article. Clinical Trial.
Disparities by Race in Pregnancy Care and Clinical Outcomes in Women With Multiple Sclerosis: A Diverse Multicenter Cohort.
Radzik AM, Amezcua L, Anderson A, Gilmore S, Ahmad S, Brandstadter R, Fabian MT, Graham EL, Hodgkinson S, Horton L, Jacobs DA, Katz Sand IB, Kohli A, Levine L, McLemore M, Okai AF, Patel J, Poole S, Riley C, Satyanarayan S, Tardo L, Verter E, Villacorta V, Zimmerman V, Zuroff L, Williams MJ, Houtchens MK, Bove R. Radzik AM, et al. Neurology. 2024 Feb 27;102(4):e208100. doi: 10.1212/WNL.0000000000208100. Epub 2024 Jan 23. Neurology. 2024. PMID: 38261988 Free PMC article.
Multiple sclerosis and the visual system.
Jacobs DA, Galetta SL. Jacobs DA, et al. Ophthalmol Clin North Am. 2004 Sep;17(3):265-73, v. doi: 10.1016/j.ohc.2004.05.011. Ophthalmol Clin North Am. 2004. PMID: 15337188 Review.
3,075 results