Lim D - Search Results

1

mTORC1 phosphorylation sites encode their sensitivity to starvation and rapamycin.

Kang SA, Pacold ME, Cervantes CL, Lim D, Lou HJ, Ottina K, Gray NS, Turk BE, Yaffe MB, Sabatini DM. Kang SA, et al. Among authors: lim d. Science. 2013 Jul 26;341(6144):1236566. doi: 10.1126/science.1236566. Science. 2013. PMID: 23888043 Free PMC article.

2

The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.

Hsu PP, Kang SA, Rameseder J, Zhang Y, Ottina KA, Lim D, Peterson TR, Choi Y, Gray NS, Yaffe MB, Marto JA, Sabatini DM. Hsu PP, et al. Among authors: lim d. Science. 2011 Jun 10;332(6035):1317-22. doi: 10.1126/science.1199498. Science. 2011. PMID: 21659604 Free PMC article.

3

Structure and function of Polo-like kinases.

Lowery DM, Lim D, Yaffe MB. Lowery DM, et al. Among authors: lim d. Oncogene. 2005 Jan 10;24(2):248-59. doi: 10.1038/sj.onc.1208280. Oncogene. 2005. PMID: 15640840 Review.

4

Activation of the yeast Hippo pathway by phosphorylation-dependent assembly of signaling complexes.

Rock JM, Lim D, Stach L, Ogrodowicz RW, Keck JM, Jones MH, Wong CC, Yates JR 3rd, Winey M, Smerdon SJ, Yaffe MB, Amon A. Rock JM, et al. Among authors: lim d. Science. 2013 May 17;340(6134):871-5. doi: 10.1126/science.1235822. Epub 2013 Apr 11. Science. 2013. PMID: 23579499 Free PMC article.

5

MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation.

Manke IA, Nguyen A, Lim D, Stewart MQ, Elia AE, Yaffe MB. Manke IA, et al. Among authors: lim d. Mol Cell. 2005 Jan 7;17(1):37-48. doi: 10.1016/j.molcel.2004.11.021. Mol Cell. 2005. PMID: 15629715 Free article.

6

Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling.

Alexander J, Lim D, Joughin BA, Hegemann B, Hutchins JR, Ehrenberger T, Ivins F, Sessa F, Hudecz O, Nigg EA, Fry AM, Musacchio A, Stukenberg PT, Mechtler K, Peters JM, Smerdon SJ, Yaffe MB. Alexander J, et al. Among authors: lim d. Sci Signal. 2011 Jun 28;4(179):ra42. doi: 10.1126/scisignal.2001796. Sci Signal. 2011. PMID: 21712545 Free PMC article.

7

Proteomic screen defines the Polo-box domain interactome and identifies Rock2 as a Plk1 substrate.

Lowery DM, Clauser KR, Hjerrild M, Lim D, Alexander J, Kishi K, Ong SE, Gammeltoft S, Carr SA, Yaffe MB. Lowery DM, et al. Among authors: lim d. EMBO J. 2007 May 2;26(9):2262-73. doi: 10.1038/sj.emboj.7601683. Epub 2007 Apr 19. EMBO J. 2007. PMID: 17446864 Free PMC article.

8

Are redox changes a critical switch for mitotic progression?

Lim DC, Joukov V, Yaffe MB. Lim DC, et al. Mol Cell Oncol. 2020 Oct 23;7(6):1832419. doi: 10.1080/23723556.2020.1832419. Mol Cell Oncol. 2020. PMID: 33235921 Free PMC article.

9

Novel Macrocyclic Peptidomimetics Targeting the Polo-Box Domain of Polo-Like Kinase 1.

Ryu S, Park JE, Ham YJ, Lim DC, Kwiatkowski NP, Kim DH, Bhunia D, Kim ND, Yaffe MB, Son W, Kim N, Choi TI, Swain P, Kim CH, Lee JY, Gray NS, Lee KS, Sim T. Ryu S, et al. Among authors: lim dc. J Med Chem. 2022 Feb 10;65(3):1915-1932. doi: 10.1021/acs.jmedchem.1c01359. Epub 2022 Jan 14. J Med Chem. 2022. PMID: 35029981 Free PMC article.

10

Redox priming promotes Aurora A activation during mitosis.

Lim DC, Joukov V, Rettenmaier TJ, Kumagai A, Dunphy WG, Wells JA, Yaffe MB. Lim DC, et al. Sci Signal. 2020 Jul 21;13(641):eabb6707. doi: 10.1126/scisignal.abb6707. Sci Signal. 2020. PMID: 32694171 Free PMC article.

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