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Validation of contrast-enhanced magnetic resonance imaging to monitor regenerative efficacy after cell therapy in a porcine model of convalescent myocardial infarction.
Malliaras K, Smith RR, Kanazawa H, Yee K, Seinfeld J, Tseliou E, Dawkins JF, Kreke M, Cheng K, Luthringer D, Ho CS, Blusztajn A, Valle I, Chowdhury S, Makkar RR, Dharmakumar R, Li D, Marbán L, Marbán E. Malliaras K, et al. Circulation. 2013 Dec 24;128(25):2764-75. doi: 10.1161/CIRCULATIONAHA.113.002863. Epub 2013 Sep 23. Circulation. 2013. PMID: 24061088 Free PMC article.
Allogeneic cardiospheres delivered via percutaneous transendocardial injection increase viable myocardium, decrease scar size, and attenuate cardiac dilatation in porcine ischemic cardiomyopathy.
Yee K, Malliaras K, Kanazawa H, Tseliou E, Cheng K, Luthringer DJ, Ho CS, Takayama K, Minamino N, Dawkins JF, Chowdhury S, Duong DT, Seinfeld J, Middleton RC, Dharmakumar R, Li D, Marbán L, Makkar RR, Marbán E. Yee K, et al. Among authors: malliaras k. PLoS One. 2014 Dec 2;9(12):e113805. doi: 10.1371/journal.pone.0113805. eCollection 2014. PLoS One. 2014. PMID: 25460005 Free PMC article.
Durable Benefits of Cellular Postconditioning: Long-Term Effects of Allogeneic Cardiosphere-Derived Cells Infused After Reperfusion in Pigs with Acute Myocardial Infarction.
Kanazawa H, Tseliou E, Dawkins JF, De Couto G, Gallet R, Malliaras K, Yee K, Kreke M, Valle I, Smith RR, Middleton RC, Ho CS, Dharmakumar R, Li D, Makkar RR, Fukuda K, Marbán L, Marbán E. Kanazawa H, et al. Among authors: malliaras k. J Am Heart Assoc. 2016 Feb 8;5(2):e002796. doi: 10.1161/JAHA.115.002796. J Am Heart Assoc. 2016. PMID: 26857066 Free PMC article.
Dedifferentiation and proliferation of mammalian cardiomyocytes.
Zhang Y, Li TS, Lee ST, Wawrowsky KA, Cheng K, Galang G, Malliaras K, Abraham MR, Wang C, Marbán E. Zhang Y, et al. Among authors: malliaras k. PLoS One. 2010 Sep 3;5(9):e12559. doi: 10.1371/journal.pone.0012559. PLoS One. 2010. PMID: 20838637 Free PMC article.
Cellular postconditioning: allogeneic cardiosphere-derived cells reduce infarct size and attenuate microvascular obstruction when administered after reperfusion in pigs with acute myocardial infarction.
Kanazawa H, Tseliou E, Malliaras K, Yee K, Dawkins JF, De Couto G, Smith RR, Kreke M, Seinfeld J, Middleton RC, Gallet R, Cheng K, Luthringer D, Valle I, Chowdhury S, Fukuda K, Makkar RR, Marbán L, Marbán E. Kanazawa H, et al. Among authors: malliaras k. Circ Heart Fail. 2015 Mar;8(2):322-32. doi: 10.1161/CIRCHEARTFAILURE.114.001484. Epub 2015 Jan 13. Circ Heart Fail. 2015. PMID: 25587096 Free PMC article.
Intracoronary cardiosphere-derived cells after myocardial infarction: evidence of therapeutic regeneration in the final 1-year results of the CADUCEUS trial (CArdiosphere-Derived aUtologous stem CElls to reverse ventricUlar dySfunction).
Malliaras K, Makkar RR, Smith RR, Cheng K, Wu E, Bonow RO, Marbán L, Mendizabal A, Cingolani E, Johnston PV, Gerstenblith G, Schuleri KH, Lardo AC, Marbán E. Malliaras K, et al. J Am Coll Cardiol. 2014 Jan 21;63(2):110-22. doi: 10.1016/j.jacc.2013.08.724. Epub 2013 Sep 11. J Am Coll Cardiol. 2014. PMID: 24036024 Free PMC article. Clinical Trial.
Intramyocardial injection of autologous cardiospheres or cardiosphere-derived cells preserves function and minimizes adverse ventricular remodeling in pigs with heart failure post-myocardial infarction.
Lee ST, White AJ, Matsushita S, Malliaras K, Steenbergen C, Zhang Y, Li TS, Terrovitis J, Yee K, Simsir S, Makkar R, Marbán E. Lee ST, et al. Among authors: malliaras k. J Am Coll Cardiol. 2011 Jan 25;57(4):455-65. doi: 10.1016/j.jacc.2010.07.049. J Am Coll Cardiol. 2011. PMID: 21251587 Free article.
Cardiac regeneration validated.
Malliaras K, Marbán E. Malliaras K, et al. Nat Biotechnol. 2015 Jun;33(6):587. doi: 10.1038/nbt.3254. Nat Biotechnol. 2015. PMID: 26057969 No abstract available.
72 results