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BIRC2/cIAP1 Is a Negative Regulator of HIV-1 Transcription and Can Be Targeted by Smac Mimetics to Promote Reversal of Viral Latency.
Pache L, Dutra MS, Spivak AM, Marlett JM, Murry JP, Hwang Y, Maestre AM, Manganaro L, Vamos M, Teriete P, Martins LJ, König R, Simon V, Bosque A, Fernandez-Sesma A, Cosford ND, Bushman FD, Young JA, Planelles V, Chanda SK. Pache L, et al. Cell Host Microbe. 2015 Sep 9;18(3):345-53. doi: 10.1016/j.chom.2015.08.009. Cell Host Microbe. 2015. PMID: 26355217 Free PMC article.
Replication competent virus as an important source of bias in HIV latency models utilizing single round viral constructs.
Bonczkowski P, De Spiegelaere W, Bosque A, White CH, Van Nuffel A, Malatinkova E, Kiselinova M, Trypsteen W, Witkowski W, Vermeire J, Verhasselt B, Martins L, Woelk CH, Planelles V, Vandekerckhove L. Bonczkowski P, et al. Retrovirology. 2014 Aug 21;11:70. doi: 10.1186/s12977-014-0070-3. Retrovirology. 2014. PMID: 25142072 Free PMC article.
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