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The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway.
Chantranupong L, Scaria SM, Saxton RA, Gygi MP, Shen K, Wyant GA, Wang T, Harper JW, Gygi SP, Sabatini DM. Chantranupong L, et al. Among authors: sabatini dm. Cell. 2016 Mar 24;165(1):153-164. doi: 10.1016/j.cell.2016.02.035. Epub 2016 Mar 10. Cell. 2016. PMID: 26972053 Free PMC article.
AMPK and p53 help cells through lean times.
Thoreen CC, Sabatini DM. Thoreen CC, et al. Among authors: sabatini dm. Cell Metab. 2005 May;1(5):287-8. doi: 10.1016/j.cmet.2005.04.009. Cell Metab. 2005. PMID: 16054073 Free article. Review.
Growing roles for the mTOR pathway.
Sarbassov DD, Ali SM, Sabatini DM. Sarbassov DD, et al. Among authors: sabatini dm. Curr Opin Cell Biol. 2005 Dec;17(6):596-603. doi: 10.1016/j.ceb.2005.09.009. Epub 2005 Oct 13. Curr Opin Cell Biol. 2005. PMID: 16226444 Review.
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB.
Sarbassov DD, Ali SM, Sengupta S, Sheen JH, Hsu PP, Bagley AF, Markhard AL, Sabatini DM. Sarbassov DD, et al. Among authors: sabatini dm. Mol Cell. 2006 Apr 21;22(2):159-68. doi: 10.1016/j.molcel.2006.03.029. Epub 2006 Apr 6. Mol Cell. 2006. PMID: 16603397 Free article.
PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase.
Sancak Y, Thoreen CC, Peterson TR, Lindquist RA, Kang SA, Spooner E, Carr SA, Sabatini DM. Sancak Y, et al. Among authors: sabatini dm. Mol Cell. 2007 Mar 23;25(6):903-15. doi: 10.1016/j.molcel.2007.03.003. Mol Cell. 2007. PMID: 17386266 Free article.
Defining the role of mTOR in cancer.
Guertin DA, Sabatini DM. Guertin DA, et al. Among authors: sabatini dm. Cancer Cell. 2007 Jul;12(1):9-22. doi: 10.1016/j.ccr.2007.05.008. Cancer Cell. 2007. PMID: 17613433 Free article. Review.
287 results