Utilization of a glucagon infusion in the management of a massive nifedipine overdose

J Emerg Med. 2000 May;18(4):453-5. doi: 10.1016/s0736-4679(00)00163-3.

Abstract

This case report describes a continuous i.v. infusion of glucagon used to reverse the cardiovascular manifestations of a nifedipine overdose in a patient who presented after a massive nifedipine extended-release tablet ingestion. In this patient, glucagon appeared to be effective in the management of this toxicologic emergency.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Calcium Channel Blockers / pharmacology
  • Calcium Channel Blockers / poisoning*
  • Delayed-Action Preparations
  • Emergency Treatment / methods*
  • Gastric Lavage
  • Glucagon / pharmacology
  • Glucagon / therapeutic use*
  • Humans
  • Hypotension / chemically induced*
  • Hypotension / diagnosis
  • Hypotension / therapy*
  • Infusions, Intravenous
  • Male
  • Middle Aged
  • Nifedipine / pharmacology
  • Nifedipine / poisoning*
  • Suicide, Attempted*

Substances

  • Calcium Channel Blockers
  • Delayed-Action Preparations
  • Glucagon
  • Nifedipine