Inhibition of Alzheimer's disease beta-amyloid aggregation, neurotoxicity, and in vivo deposition by nitrophenols: implications for Alzheimer's therapy

FASEB J. 2001 May;15(7):1297-9. doi: 10.1096/fj.00-0676fje.
No abstract available

MeSH terms

  • Alzheimer Disease / drug therapy
  • Alzheimer Disease / metabolism*
  • Amyloid beta-Peptides / chemistry
  • Amyloid beta-Peptides / metabolism*
  • Animals
  • Cells, Cultured
  • Hippocampus / cytology
  • Hippocampus / drug effects*
  • Hippocampus / metabolism
  • Humans
  • Microinjections
  • Neurons / cytology
  • Neurons / drug effects*
  • Neurons / metabolism
  • Neuroprotective Agents / pharmacology*
  • Nitrophenols / pharmacology*
  • Protein Structure, Tertiary
  • Rats

Substances

  • Amyloid beta-Peptides
  • Neuroprotective Agents
  • Nitrophenols