Editing machines: the complexities of trypanosome RNA editing

Susan Madison-Antenucci; Jayleen Grams; Stephen L Hajduk

doi:10.1016/s0092-8674(02)00653-0

Editing machines: the complexities of trypanosome RNA editing

Cell. 2002 Feb 22;108(4):435-8. doi: 10.1016/s0092-8674(02)00653-0.

Authors

Susan Madison-Antenucci¹, Jayleen Grams, Stephen L Hajduk

Affiliation

¹ Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Schools of Medicine and Dentistry, Birmingham, AL 35294, USA.

PMID: 11909515
DOI: 10.1016/s0092-8674(02)00653-0

Abstract

The assembly and disassembly of ribonucleoprotein complexes containing substrate precursor mRNAs and guide RNAs is crucial to the initiation and propagation of RNA editing. We discuss here the composition of these complexes and how their assembly may regulate RNA editing.

Publication types

Review

MeSH terms

Animals
Macromolecular Substances
Mitochondria / genetics*
Mitochondria / metabolism
Models, Genetic
RNA Editing / genetics*
Ribonucleoproteins / metabolism*
Trypanosoma / cytology
Trypanosoma / genetics*
Trypanosoma / metabolism

Substances

Macromolecular Substances
Ribonucleoproteins