First case of post-conception Verteporfin exposure: pregnancy and neonatal outcome

Acta Ophthalmol Scand. 2004 Oct;82(5):623-4. doi: 10.1111/j.1600-0420.2004.00247.x.

Abstract

Purpose: To assess pregnancy and neonatal outcomes in a woman accidentally exposed to Verteporfin photodynamic therapy in the third week of pregnancy.

Methods: Post-conception counselling and prospective follow-up by telephone interview at Telefono Rosso (Teratology Information Service) were carried out. The baby was examined at birth and at 26 months.

Results: The outcome of the pregnancy was normal and a healthy female child with a normal birthweight was born. The baby's follow-up was normal at 26 months.

Conclusions: This is the first reported case of a childbearing woman being accidentally exposed to Verteporfin during pregnancy. No fetal or neonatal adverse effects were documented.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Choroidal Neovascularization / drug therapy*
  • Female
  • Fertilization*
  • Humans
  • Infant, Newborn
  • Photochemotherapy*
  • Photosensitizing Agents / therapeutic use*
  • Porphyrins / therapeutic use*
  • Pregnancy
  • Pregnancy Outcome*
  • Verteporfin

Substances

  • Photosensitizing Agents
  • Porphyrins
  • Verteporfin