Abstract
Six lignans including a new lignan (1), beta-sitosterol glucopyranoside and phenylpropanoids were isolated from the whole plants of Balanophora abbreviata Bl. (Balanophoraceae). Their structures were determined by NMR, MS analysis and other spectroscopic methods. Lignans (1, 2 and 4) showed potent inhibitory activities on the lipopolysaccharide (LPS)-induced inducible nitric oxide synthase (iNOS) expression in RAW 264.7 cells.
MeSH terms
-
Animals
-
Balanophoraceae*
-
Cell Line, Tumor
-
Lignans / chemistry*
-
Lignans / isolation & purification
-
Lignans / pharmacology*
-
Lipopolysaccharides / pharmacology
-
Magnetic Resonance Spectroscopy
-
Mass Spectrometry
-
Mice
-
Molecular Structure
-
Nitric Oxide Synthase / antagonists & inhibitors*
-
Nitric Oxide Synthase / biosynthesis
-
Nitric Oxide Synthase Type II
-
Plant Extracts / chemistry
Substances
-
Lignans
-
Lipopolysaccharides
-
Plant Extracts
-
Nitric Oxide Synthase
-
Nitric Oxide Synthase Type II
-
Nos2 protein, mouse