[Prognostic morbidity and mortality factors in hospital enteral nutrition: prospective study]

Nutr Hosp. 2005 May-Jun;20(3):210-6.
[Article in Spanish]

Abstract

Objective: To determine the prognostic factors that may best for see the outcome of an enteral nutritional intervention and to assess the assistance quality of a nutrition unit.

Setting and subjects: Patients that required enteral nutrition during hospital admission at a third level center.

Interventions: Observational prospective study in which 160 patients were included by means of consecutive sampling, for a 6-months follow-up period. Underlying pathology, disability degree, nutritional assessment, type of enteral nutrition, complications, nursing care, and clinical course of patients were determined.

Results: severe caloric and protein hyponutrition was diagnosed in 48.4 and 52.9% of patients; stress degree was moderate in 52.2% and severe in 36.5%. In 88.2% of patients variation of protein parameters was unchanged or improved, with a 0.26 g/dL increase in albumin levels and 2.4 m/dL in prealbumin (p < 0.05). Multivariate analysis adjusted for plasma albumin at admission showed that besides this biochemical parameter, a severe stress degree, a decreased alertness level, and worsening of protein variation during admission are independent prognostic mortality factors during an enteral nutritional intervention in the hospitalized patient (p < 0.05).

Conclusions: alertness level, degree of caloric hyponutrition, stress degree, plasma albumin levels, and variation of protein parameters during nutritional support are independent prognostic factors for the nutritional intervention outcomes. The development of global monitoring systems of assistance activity and quality of Nutrition Units is paramount in order to improve the efficiency of enteral nutritional support at the hospital setting, to advance in patients care and promote the development of nutritional therapy.

Publication types

  • English Abstract

MeSH terms

  • Enteral Nutrition*
  • Female
  • Hospitalization*
  • Humans
  • Male
  • Malnutrition / complications
  • Malnutrition / mortality
  • Malnutrition / therapy*
  • Middle Aged
  • Prognosis
  • Prospective Studies