Room-specific characteristics of suburban homes as predictors of indoor allergen concentrations

Ann Allergy Asthma Immunol. 2006 Nov;97(5):628-35. doi: 10.1016/S1081-1206(10)61092-7.

Abstract

Background: Room characteristics predicting indoor allergen exposure in suburban homes have not been clearly identified.

Objective: To examine relationships between room characteristics and concentrations of indoor allergens in homes of suburban asthmatic patients.

Methods: The homes of 339 asthmatic children ages 6 to 17 years were studied. Home inspections were conducted by a trained technician, and dust samples were analyzed for indoor allergen content. A high allergen concentration was defined as 8 microg (U)/g or more of fine dust.

Results: Infrequent sheet washing and wall-to-wall carpet were risk factors for high bedroom dust mite concentrations. Infrequent sheet washing was also a risk factor for high Fel d 1 concentrations. Food remains in the bedroom was a risk factor for high bedroom Bla g 1 levels, and exposed food, leaks, and dirty pots were all risk factors for high kitchen Bla g 1 levels. The combination of lack of mattress or pillow encasements, infrequent sheet washing, and carpeting was associated with a 24-fold increase in odds of a high dust mite concentration (odds ratio [OR], 24.1; 95% confidence interval [CI], 3.2-181.4). Among non-cat owners, the combination of stuffed toys on the bed, lack of mattress or pillow encasements, and infrequent sheet washing was associated with a 49-fold increase in odds of a high Fel d 1 level (OR, 49.4; 95% CI, 2.8-887.3). The combination of leaks, exposed food, and dirty pots was associated with a high kitchen Bla g 1 concentration (OR, 10.6; 95% CI, 2.8-40.5).

Conclusions: Specific room characteristics predict high indoor allergen exposure among children with asthma, and a combination of these characteristics may further increase the risk of high allergen exposure.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adolescent
  • Air Pollution, Indoor / analysis*
  • Allergens / analysis*
  • Animals
  • Animals, Domestic
  • Antigens, Dermatophagoides / analysis
  • Antigens, Plant
  • Asthma / epidemiology*
  • Asthma / etiology
  • Cats
  • Child
  • Dogs
  • Dust / analysis
  • Environmental Exposure / adverse effects
  • Environmental Exposure / analysis
  • Female
  • Glycoproteins / analysis
  • Housing*
  • Humans
  • Male
  • Maryland / epidemiology
  • Odds Ratio
  • Risk Factors
  • Skin Tests
  • Suburban Population*
  • Surveys and Questionnaires

Substances

  • Allergens
  • Antigens, Dermatophagoides
  • Antigens, Plant
  • Dust
  • Glycoproteins
  • allergen Bla g 1
  • allergen Can f I
  • Fel d 1 protein, Felis domesticus