[Digital ischemia related to bromocriptin]

Rev Med Interne. 2008 Oct;29(10):805-7. doi: 10.1016/j.revmed.2008.03.007. Epub 2008 Jun 24.
[Article in French]

Abstract

Introduction: Bromocriptin has been associated with stroke and myocardial infarction in the postpartum period. We report on the case of a patient who developed digital ischemia while receiving this drug.

Exegesis: Mrs D, 28 years old presented with digital ischemia occurring five days after the introduction of bromocriptin. Magnetic resonance imaging also displayed stroke in the area of the right posterior cerebellar artery. The course was favourable after discontinuation of the drug.

Discussion: Bromocriptin is an ergot derivative with dopaminergic agonist properties. A paradoxical vasoconstriction is rarely associated with vascular ischemic complications, including digital ischemia.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Bromocriptine / administration & dosage
  • Bromocriptine / adverse effects*
  • Depression, Postpartum / drug therapy
  • Dopamine Agonists / administration & dosage
  • Dopamine Agonists / adverse effects*
  • Female
  • Fingers / blood supply*
  • Humans
  • Ischemia / chemically induced*

Substances

  • Dopamine Agonists
  • Bromocriptine