Second opinions improve ADHD prescribing in a medicaid-insured community population

J Am Acad Child Adolesc Psychiatry. 2009 Jul;48(7):740-748. doi: 10.1097/CHI.0b013e3181a2b2ed.

Abstract

Objective: The appropriate use of psychotropic medications in youths is an important public health concern. In this article, we describe a review process developed to monitor the use of stimulants and atomoxetine for attention-deficit/hyperactivity syndrome (ADHD) in youths receiving fee-for-service Medicaid services.

Method: Washington State Medicaid developed threshold safety parameters for ADHD medications through a process involving the community. A second opinion was mandated when safety thresholds based on dose, combination therapies, or age was exceeded. Use and cost were compared 2 years before and after the program began.

Results: From May 2006 to April 2008, 5.35% of ADHD prescriptions exceeded safety thresholds, resulting in 1,046 second-opinion reviews. Of those, 538 (51.4%) resulted in a prescription adjustment. Adjustments were made to primary care physician (52%), psychiatrist (50%), nurse practitioner (54%), and physician assistant-written (51%) prescriptions. When the preperiod and postperiod were compared, second opinions reduced ADHD medication at high doses (53%), in combinations (44%), and for patients 5 years of age and younger (23%). The review process resulted in a savings of $1.2 million, with 538 fewer patients exceeding safety thresholds. This was a 10:1 return over administrative costs; however, the overall Medicaid expenditures for ADHD medication still increased because of higher unit costs and the preferential use by clinicians of newer brands entering the market.

Conclusions: A statewide second-opinion process reduced outlier ADHD medication prescription practices and was cost-effective. Suggestions for process and quality improvements in prescribing to children diagnosed with ADHD are discussed.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adolescent
  • Adrenergic Uptake Inhibitors / administration & dosage*
  • Adrenergic Uptake Inhibitors / adverse effects
  • Adrenergic Uptake Inhibitors / economics
  • Atomoxetine Hydrochloride
  • Attention Deficit Disorder with Hyperactivity / diagnosis
  • Attention Deficit Disorder with Hyperactivity / drug therapy*
  • Attention Deficit Disorder with Hyperactivity / economics
  • Central Nervous System Stimulants / economics
  • Central Nervous System Stimulants / therapeutic use*
  • Child
  • Child, Preschool
  • Cost Savings / statistics & numerical data
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Drug Costs / statistics & numerical data
  • Drug-Related Side Effects and Adverse Reactions / economics
  • Evidence-Based Medicine
  • Female
  • Health Expenditures / statistics & numerical data
  • Humans
  • Male
  • Medicaid* / economics
  • Propylamines / administration & dosage*
  • Propylamines / adverse effects
  • Propylamines / economics
  • Referral and Consultation* / economics
  • Treatment Outcome
  • United States
  • Washington

Substances

  • Adrenergic Uptake Inhibitors
  • Central Nervous System Stimulants
  • Propylamines
  • Atomoxetine Hydrochloride