Persistent agmination of lymphomatoid papulosis

Pediatr Dermatol. 2009 Nov-Dec;26(6):762-4. doi: 10.1111/j.1525-1470.2009.01035.x.

Abstract

A 12-year-old boy had lesions clinically and histopathologically consistent with lymphomatoid papulosis (LP) which were persistent and appeared grouped in a circumscribed area of normal looking background skin on the right abdomen. Staging work-up did not disclose systemic disease. Persistent agmination of lymphomatoid papulosis (PALP) is somewhat different from classical LP because it involves a circumscribed, patch-sized area of the skin and the papules within never resolve completely despite some waxing and waning. PALP might be considered a localized or regional form of LP or a distinct lymphoproliferative disorder; in any case, at least a cautious long-term follow up is recommended, with attention to the possible development of true lymphoma.

Publication types

  • Case Reports

MeSH terms

  • Biopsy
  • Child
  • Humans
  • Ki-1 Antigen / metabolism
  • Lymphomatoid Papulosis / metabolism
  • Lymphomatoid Papulosis / pathology*
  • Male
  • Skin / metabolism
  • Skin / pathology*
  • Skin Neoplasms / metabolism
  • Skin Neoplasms / pathology*

Substances

  • Ki-1 Antigen