Obesity epidemics is a growing medical problem all over the world. Obesity is an independent atherosclerosis risk factor. Commonly known risk factors don't fully explains increased coronary artery disease risk in this group of patients. One of the potential mechanisms responsible for the direct influence of obesity on atherosclerosis progression is impaired oxidation-antioxidation balance estimated by TAS (Total Antioxidant Status). The aim of study was to evaluate the regular physical activity influence on oxidative stress activity in women with simple obesity.
Material and methods: 20 women with simple obesity, aged 23-65 years, were studied. All of them underwent a 6-month physical activity programme under the observation of a physiotherapist. Before and after the programme TAS, lipid profile and C-reactive protein concentration were assessed.
Results: After 6 months of the physical therapy programme a significant increase of TAS was found. Favorable changes in biochemical parameters were accompanied by decrease of waist circumference. Positive correlation between change in waist circumference and change in TAS was observed.
Conclusions: Obesity in women increases inflammatory process activity. Regular physical activity favorably influence lipids parameters and blood pressure. Regular physical activity in obese women increases total antioxidant capacity, mainly related to waist circumference reduction.