Abstract
To analyze the molecular epidemiology of Mycobacterium tuberculosis strains at a hospital in Buenos Aires, Argentina, and mutations related to multidrug-resistant and extensively drug-resistant tuberculosis, we conducted a prospective case-control study. Our findings reinforce the value of incorporating already standardized molecular methods for rapidly detecting resistance.
MeSH terms
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Antitubercular Agents / pharmacology
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Antitubercular Agents / therapeutic use
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Argentina / epidemiology
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Bacterial Proteins / genetics
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Case-Control Studies
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Drug Resistance, Multiple, Bacterial / genetics
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Extensively Drug-Resistant Tuberculosis / epidemiology
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Extensively Drug-Resistant Tuberculosis / microbiology
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Female
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Humans
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Male
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Microbial Sensitivity Tests
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Molecular Epidemiology*
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Mutation
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Mycobacterium tuberculosis / classification
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Mycobacterium tuberculosis / drug effects
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Mycobacterium tuberculosis / genetics*
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Mycobacterium tuberculosis / isolation & purification
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Prospective Studies
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Tuberculosis / epidemiology*
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Tuberculosis / microbiology
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Tuberculosis, Multidrug-Resistant / epidemiology*
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Tuberculosis, Multidrug-Resistant / microbiology
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Tuberculosis, Pulmonary / epidemiology*
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Tuberculosis, Pulmonary / microbiology
Substances
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Antitubercular Agents
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Bacterial Proteins