Marked for translation: long A/U tails as an interface between completion of RNA editing and ribosome recruitment

Laurie K Read; Sara L Zimmer; Michelle L Ammerman

doi:10.1016/j.molcel.2011.03.013

Marked for translation: long A/U tails as an interface between completion of RNA editing and ribosome recruitment

Mol Cell. 2011 Apr 8;42(1):6-8. doi: 10.1016/j.molcel.2011.03.013.

Authors

Laurie K Read¹, Sara L Zimmer, Michelle L Ammerman

Affiliation

¹ Department of Microbiology and Immunology, SUNY Buffalo School of Medicine, Buffalo, NY 14214, USA. lread@buffalo.edu

PMID: 21474064
DOI: 10.1016/j.molcel.2011.03.013

Abstract

The mechanism by which ribosomes select translatable mRNAs from the complex mixture of incompletely edited mRNAs in trypanosome mitochondria has remained a mystery. In this issue of Molecular Cell, Aphasizheva and colleagues (Aphasizheva et al., 2011) reveal a role for long 3' A/U tails in signaling ribosome recruitment to a fully edited, translatable mRNA.

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