Surgical strategy for aortic coarctation repair resulting in physiologic arm and leg blood pressures

Congenit Heart Dis. 2011 Nov-Dec;6(6):583-91. doi: 10.1111/j.1747-0803.2011.00589.x. Epub 2011 Nov 3.

Abstract

Objective: The goal of aortic coarctation repair is laminar aortic blood flow resulting in a negative or absent arm:leg blood pressure (BP) gradient. Despite satisfactory relief of coarctation, associated arch hypoplasia can result in residual obstruction and postoperative upper body hypertension.

Intervention: We devised a surgical strategy to create a tension-free anastomosis with a diameter as large as both the adjacent proximal and distal aorta using a radically extended end-to-end anastomosis via sternotomy and/or thoracotomy. Sternotomy is chosen when there is significant transverse arch hypoplasia defined as a distal transverse arch ≤ diameter of the left carotid artery, presence of a common brachiocephalic trunk, or coexisting intracardiac lesion requiring repair. Thoracotomy is used in all other cases.

Results: From 2000 to 2008, 95 consecutive patients were repaired using this approach, 35 with sternotomy and 60 with thoracotomy. At a mean follow-up of 50 ± 23 months, mean systolic BP was 94 ± 10 mm Hg, and 84% of patients had no residual arm:leg BP gradient. Mean arm:leg BP gradient was not statistically different between groups (-8.5 ± 15 sternotomy and -7.0 ± 10 mm Hg thoracotomy, P= .7). With Doppler echocardiography, 96% of patients demonstrated normal early diastolic reversal of blood flow in the descending thoracic aorta.

Conclusions: For aortic coarctation repair in infancy, a strategy designed to directly address aortic arch hypoplasia results in excellent intermediate-term results with normal BP, physiologic arm:leg BP relationship, and near normal descending aortic blood flow velocities by Doppler.

Publication types

  • Multicenter Study

MeSH terms

  • Aorta / diagnostic imaging
  • Aorta / physiopathology
  • Aorta / surgery*
  • Aortic Coarctation / complications
  • Aortic Coarctation / diagnostic imaging
  • Aortic Coarctation / physiopathology
  • Aortic Coarctation / surgery*
  • Blood Flow Velocity
  • Blood Pressure*
  • Cardiac Surgical Procedures* / adverse effects
  • Chi-Square Distribution
  • Echocardiography, Doppler
  • Female
  • Humans
  • Hypertension / diagnostic imaging
  • Hypertension / etiology
  • Hypertension / physiopathology
  • Hypertension / surgery*
  • Infant
  • Infant, Newborn
  • Kaplan-Meier Estimate
  • Lower Extremity / blood supply*
  • Male
  • New York
  • Regional Blood Flow
  • Retrospective Studies
  • Sternotomy* / adverse effects
  • Thoracotomy* / adverse effects
  • Time Factors
  • Treatment Outcome
  • Upper Extremity / blood supply*