Folate and vitamin B12 status in schizophrenic patients

J Res Med Sci. 2011 Mar;16 Suppl 1(Suppl1):S437-41.

Abstract

Background: This study aimed to determine red blood cell (RBC) and serum folate and vitamin B12 levels as well as their intake in schizophrenic patients.

Methods: The folate and cobalamin status of 60 schizophrenic patients (15-55 years) was compared to 60 matched healthy controls using Radio Isotope Dilution Assay (RIDA).

Results: Serum and RBC folate in schizophrenic patients was significantly lower than the control group. Mean serum cobalamin levels in the schizophrenic group were higher than controls.

Conclusions: This study showed that folate deficiency is common in schizophrenic patients; therefore, it is important to pay attention to folate levels in these patients.

Keywords: Eating; Folic Acid; Schizophrenia; Vitamin B12.