Variation in use of dual-chamber implantable cardioverter-defibrillators: results from the national cardiovascular data registry

Arch Intern Med. 2012 Apr 23;172(8):634-41; discussion 641. doi: 10.1001/archinternmed.2012.394.

Abstract

Background: Among patients without an indication for a pacemaker, current evidence is inconclusive whether a dual-chamber implantable cardioverter-defibrillator (ICD) is superior to a single-chamber ICD. The current use of dual-chamber ICDs is not well characterized.

Methods: We conducted a cross-sectional study exploring hospital-level variation in the use of dual-chamber ICDs across the United States. Patients receiving a primary prevention ICD from 2006 through 2009 without a documented indication for a pacemaker were included. Multivariate hierarchical logistic regression was used to explore patient, health care provider, and physician factors related to the use of a dual-chamber device.

Results: Dual-chamber devices were implanted in 58% of the 87,115 patients without a pacing indication among 1293 hospitals, with hospital rates ranging from 0% in 33 centers to 100% in 109 centers. In multivariate analysis, geographic region was a strong independent predictor of dual-chamber device use, ranging from 36.4% in New England (reference region) to 66.4% in the Pacific region (odds ratio [OR], 5.25; 95% CI, 3.35-8.21). Hospital clustering was assessed using a median OR which was 3.96, meaning that 2 identical patients at different hospitals would have nearly a 4-fold difference in their chance of receiving a dual-chamber ICD.

Conclusions: Use of dual-chamber ICDs for the primary prevention of sudden cardiac death among patients without an indication for permanent pacing varies markedly at the hospital level in the United States. This is a clear example of how practice can vary independent of patient factors.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Cluster Analysis
  • Comorbidity
  • Cross-Sectional Studies
  • Death, Sudden, Cardiac / epidemiology*
  • Death, Sudden, Cardiac / ethnology
  • Death, Sudden, Cardiac / prevention & control*
  • Defibrillators, Implantable / statistics & numerical data*
  • Equipment Design
  • Female
  • Hospitals / statistics & numerical data*
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Multivariate Analysis
  • New England / epidemiology
  • Odds Ratio
  • Pacemaker, Artificial
  • Pacific States / epidemiology
  • Predictive Value of Tests
  • Primary Prevention* / methods
  • Registries