Abstract
The effect of reamberin (1.5% solution of succinic acid and ion complex) on the oxygenation status of the brain was studied in children aged 1 - 14 years during recovery from anesthesia. It is established that reamberin in a dose of 2 ml/kg administered twice at the end of an operation increases the fraction of oxidized hemoglobin and cytochrome oxidase and enhances the regional saturation of brain tissue with oxygen, which is indicative of an increase in the potential of metabolism activation in neurons.
MeSH terms
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Adolescent
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Anesthesia
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Anesthesia Recovery Period
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Anesthetics / administration & dosage
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Brain / drug effects*
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Brain / metabolism
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Child
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Child, Preschool
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Drug Administration Schedule
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Electron Transport Complex IV / biosynthesis
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Humans
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Infant
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Injections, Intravenous
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Male
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Meglumine / administration & dosage
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Meglumine / analogs & derivatives*
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Meglumine / therapeutic use
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Neurons / drug effects*
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Neurons / metabolism
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Oxidation-Reduction
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Oxygen / metabolism*
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Oxygen Consumption / drug effects*
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Oxyhemoglobins / biosynthesis
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Succinates / administration & dosage*
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Succinates / therapeutic use
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Succinic Acid / chemistry
Substances
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Anesthetics
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Oxyhemoglobins
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Reamberin
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Succinates
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Meglumine
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Succinic Acid
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Electron Transport Complex IV
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Oxygen