Risk for contrast-induced nephropathy in elderly trauma patients

Am Surg. 2012 Oct;78(10):1114-7.

Abstract

The objective of this study was to determine if elderly trauma patients are at risk for contrast-induced nephropathy (CIN). A retrospective study was conducted identifying 362 patients 65 years and older in our Level I trauma center who received computerized tomography (CT) scans with intravenous contrast. CIN was defined as a 25 per cent increase in serum creatinine levels or a 0.5 mg/dL increase above baseline after CT. History of diabetes mellitus, hospital length of stay, intensive care unit length of stay, Injury Severity Score (ISS), and age were recorded. Eighteen per cent (21 of 118) of the patients had a peak in creatinine, 12 per cent (14 of 118) peaked and returned to baseline, and 6 per cent (7 of 118) peaked and stayed high. Pre-CT elevated creatinine, diabetes mellitus, increased hospital length of stay, ISS, and age show little association to CIN. The data suggest that CIN in elderly trauma patients is rare, regardless of history of diabetes mellitus, age, creatinine, high ISS, or result in higher length of stay. Therefore, there is little justification for the delay in diagnosis to assess a patient's renal susceptibility.

MeSH terms

  • Aged
  • Contrast Media / adverse effects*
  • Creatinine / blood
  • Humans
  • Kidney Diseases / blood
  • Kidney Diseases / chemically induced*
  • Retrospective Studies
  • Risk Factors
  • Tomography, X-Ray Computed*

Substances

  • Contrast Media
  • Creatinine