Benign clinical course in H1N1 2009 influenza infection in young oseltamivir-treated immunocompromised patients with kidney disease in Singapore

Pediatr Infect Dis J. 2013 Mar;32(3):298-300. doi: 10.1097/INF.0b013e31827d77dc.

Abstract

This report describes the clinical features of H1N1 2009 influenza infection in 10 young renal patients receiving chronic dialysis or immunosuppressants, and to compare their durations of viral shedding with 20 healthy controls. Although patients shed the virus for longer periods compared with controls, all had a self-limited clinical course. Studies on indications, dosages and durations of antiviral therapy in renal and immunocompromised patients are warranted.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Antiviral Agents / administration & dosage*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Immunocompromised Host*
  • Influenza A Virus, H1N1 Subtype / isolation & purification*
  • Influenza, Human / drug therapy*
  • Influenza, Human / pathology*
  • Influenza, Human / virology
  • Kidney Diseases / complications*
  • Kidney Diseases / therapy
  • Male
  • Oseltamivir / administration & dosage*
  • Renal Dialysis
  • Singapore
  • Time Factors
  • Treatment Outcome
  • Virus Shedding
  • Young Adult

Substances

  • Antiviral Agents
  • Oseltamivir