Dynamin: membrane scission meets physics

Curr Biol. 2012 Dec 18;22(24):R1047-8. doi: 10.1016/j.cub.2012.11.008.

Abstract

Dynamin hydrolyzes GTP to constrict and sever membranes. Experimental advances bring dynamin into the realm of physics and reveal key roles for membrane tension and bending at the edge of the constriction.

MeSH terms

  • Cell Membrane / metabolism
  • Cryoelectron Microscopy
  • Dynamins / metabolism*
  • Dynamins / ultrastructure
  • Guanosine Triphosphate / metabolism
  • Hydrolysis
  • Magnetic Resonance Spectroscopy

Substances

  • Guanosine Triphosphate
  • Dynamins