Cognitive ability in children with chronic granulomatous disease: a comparison of those managed conservatively with those who have undergone hematopoietic stem cell transplant

Neuropediatrics. 2013 Aug;44(4):230-2. doi: 10.1055/s-0033-1333875. Epub 2013 Feb 8.

Abstract

Chronic granulomatous disease (CGD) is a primary immunodeficiency managed conservatively or with hematopoietic stem cell transplant. Studies have shown people with CGD and those transplanted for primary immunodeficiencies have lower than average cognitive ability. In this study, IQ in children with CGD and those transplanted for it was within the normal range.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cognition Disorders / etiology*
  • Cognition Disorders / surgery*
  • Granulomatous Disease, Chronic / complications*
  • Granulomatous Disease, Chronic / surgery*
  • Hematopoietic Stem Cell Transplantation / methods*
  • Humans
  • Ireland
  • Male
  • Neuropsychological Tests
  • Treatment Outcome
  • United Kingdom