Disseminated infection by Mycobacterium sherrisii and Histoplasma capsulatum in an African HIV-infected patient

Am J Trop Med Hyg. 2013 May;88(5):914-7. doi: 10.4269/ajtmh.12-0572. Epub 2013 Feb 18.

Abstract

Mycobacterium sherrisii is a new species of opportunistic, slow-growing, non-tuberculous Mycobacterium closely related to Mycobacterium simiae that can currently be identified with the sequence of 16S rARN gene and the heat-shock protein 65. Few cases of patients infected by this Mycobacterium have been reported and all of them were associated with human immunodeficiency virus or other immunosuppressive conditions. Clinical management is complex, because there is not a clear correlation between the in vitro antibiotic susceptibility testing and the patient's clinical outcome.

Publication types

  • Case Reports

MeSH terms

  • AIDS-Related Opportunistic Infections / diagnosis
  • AIDS-Related Opportunistic Infections / microbiology*
  • Adult
  • Antiretroviral Therapy, Highly Active
  • Bacterial Proteins / genetics
  • Chaperonin 60 / genetics
  • HIV Infections / complications*
  • HIV Infections / drug therapy
  • HIV Infections / virology
  • Heat-Shock Proteins / genetics
  • Histoplasma / isolation & purification
  • Histoplasmosis / complications*
  • Histoplasmosis / microbiology
  • Humans
  • Male
  • Mycobacterium / classification*
  • Mycobacterium / genetics*
  • Mycobacterium / isolation & purification
  • Mycobacterium Infections / complications*
  • Mycobacterium Infections / diagnosis
  • Mycobacterium Infections / microbiology
  • RNA, Ribosomal, 16S / genetics

Substances

  • Bacterial Proteins
  • Chaperonin 60
  • Heat-Shock Proteins
  • RNA, Ribosomal, 16S
  • heat-shock protein 65, Mycobacterium