[Granulosa cell tumors of the ovary]

Sakina Sekkate; Mouna Kairouani; Badr Serji; Hind M'Rabti; Ibrahim El Ghissassi; Hassan Errihani

doi:10.1684/bdc.2013.1879

[Granulosa cell tumors of the ovary]

Bull Cancer. 2014 Jan 1;101(1):93-101. doi: 10.1684/bdc.2013.1879.

[Article in French]

Authors

Sakina Sekkate¹, Mouna Kairouani¹, Badr Serji², Hind M'Rabti¹, Ibrahim El Ghissassi¹, Hassan Errihani¹

Affiliations

¹ Institut national d'oncologie, service d'oncologie médicale, avenue Allal el fassi, BP 10100, Rabat, Maroc.
² Hôpital IBN SINA, service de chirurgie « A », Rabat, Maroc.

PMID: 24445864
DOI: 10.1684/bdc.2013.1879

Abstract

Ovarian granulosa cell tumors (TGO) are rare neoplasms. They arise from sex cord stromal cells of the ovaries. They are characterized by their slow natural history, and their tendency to relapse long time after the initial diagnosis. Complete staging surgery of the disease is the cornerstone of treatment. Chemotherapy is indicated for localized tumors with a high risk of recurrence, and for recurrent or advanced tumors. Prolonged follow-up is recommended.

Keywords: cancer; chemotherapy; granulosa cell tumors; ovary; prognosis; surgery.

Publication types

English Abstract
Review

MeSH terms

Age Factors
Antineoplastic Agents / therapeutic use
Antineoplastic Agents, Hormonal / therapeutic use
Biomarkers, Tumor / metabolism
Diagnosis, Differential
Female
Granulosa Cell Tumor* / genetics
Granulosa Cell Tumor* / pathology
Granulosa Cell Tumor* / radiotherapy
Granulosa Cell Tumor* / therapy
Humans
Molecular Targeted Therapy / methods
Rare Diseases* / pathology
Rare Diseases* / therapy

Substances

Antineoplastic Agents
Antineoplastic Agents, Hormonal
Biomarkers, Tumor

Supplementary concepts

Granulosa cell tumor of the ovary