Macrophage activation: glancing into diversity

Gioacchino Natoli; Silvia Monticelli

doi:10.1016/j.immuni.2014.01.004

Macrophage activation: glancing into diversity

Immunity. 2014 Feb 20;40(2):175-7. doi: 10.1016/j.immuni.2014.01.004.

Authors

Gioacchino Natoli¹, Silvia Monticelli²

Affiliations

¹ Department of Experimental Oncology, European Institute of Oncology (IEO), Milan 20141, Italy. Electronic address: gioacchino.natoli@ieo.eu.
² Institute for Research in Biomedicine (IRB), 6500 Bellinzona, Switzerland. Electronic address: silvia.monticelli@irb.usi.ch.

PMID: 24560195
DOI: 10.1016/j.immuni.2014.01.004

Abstract

Macrophage activation is a crucial process for innate immunity as well as for tissue and metabolic homeostasis. In this issue of Immunity, Xue et al. (2014) extend our knowledge on macrophage activation and identify unique functional states, thus expanding the M1-M2 paradigm.

Publication types

Comment

MeSH terms

Animals
Gene Expression Profiling*
Humans
Macrophage Activation / immunology*
Models, Biological*
Transcriptome / genetics*