Abstract
We evaluated the effectiveness of daily chlorhexidine gluconate (CHG) bathing in decreasing skin carriage of Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae (KPC) among long-term acute care hospital patients. CHG bathing reduced KPC skin colonization, particularly when CHG skin concentrations greater than or equal to 128 μg/mL were achieved.
Publication types
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Evaluation Study
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Bacterial Proteins / biosynthesis*
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Baths / methods*
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Chlorhexidine / administration & dosage
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Chlorhexidine / analogs & derivatives*
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Chlorhexidine / therapeutic use
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Female
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Hospitalization
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Humans
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Klebsiella Infections / prevention & control*
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Klebsiella pneumoniae / drug effects
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Klebsiella pneumoniae / enzymology*
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Klebsiella pneumoniae / isolation & purification
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Male
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Middle Aged
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Skin / microbiology*
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beta-Lactamases / biosynthesis*
Substances
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Bacterial Proteins
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beta-Lactamases
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carbapenemase
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chlorhexidine gluconate
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Chlorhexidine