Clinical and quality-of-life outcomes following gland-preserving surgery for chronic sialadenitis

Laryngoscope. 2015 Jun;125(6):1340-4. doi: 10.1002/lary.25062. Epub 2014 Nov 25.

Abstract

Objectives/hypothesis: Gland-preserving salivary surgery utilizing salivary endoscopy has been proposed as a treatment alternative in the management of chronic sialadenitis. This study seeks to determine medium-term clinical and quality-of-life (QOL) outcomes following a gland-preserving approach for chronic sialadenitis.

Study design: Cross-sectional survey with retrospective chart review.

Methods: All patients undergoing attempted gland-preserving salivary surgery with salivary endoscopy for chronic sialadenitis at a tertiary, academic salivary referral center between October 2008 and April 2013 were identified from a quality assurance database. A research database was constructed to examine clinical factors of interest. A clinical outcomes and QOL survey was mailed to all eligible patients in order to obtain long-term follow-up data.

Results: A total of 206 of 306 (67%) eligible patients returned the survey. The median length of follow-up was 17 months (3-54 months). The majority of patients (89%) endorsed symptom improvement after gland-preserving therapy. Surgical excision was performed on 8% of affected glands. Patients with chronic sialadenitis due to stones reported a greater incidence of symptom resolution (P = 0.0004) and more favorable QOL outcomes (P = 0.0001) than patients with nonstone etiologies.

Conclusions: Patients undergoing gland-preserving salivary surgery with salivary endoscopy for chronic sialadenitis have favorable long-term symptom improvement and gland retention rates. Although patients with stones demonstrated the best outcomes, improvement was documented for all etiologies of chronic sialadenitis.

Level of evidence: 4.

Keywords: Sialadenitis; chronic sialadenitis; quality of life; salivary endoscopy; salivary stone; sialendoscopy; sialolithiasis.

Publication types

  • Evaluation Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Endoscopy*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Organ Sparing Treatments* / methods
  • Quality of Life*
  • Retrospective Studies
  • Salivary Glands*
  • Sialadenitis / surgery*
  • Treatment Outcome
  • Young Adult