Evaluation of latent tuberculous infection and treatment completion for refugees in Philadelphia, PA, 2010-2012

Int J Tuberc Lung Dis. 2015 May;19(5):565-9. doi: 10.5588/ijtld.14.0729.

Abstract

Setting: Philadelphia, PA, USA.

Objectives: To compare the evaluation and treatment of latent tuberculous infection (LTBI) in refugees seen at member clinics of the Philadelphia Refugee Health Collaborative (PRHC) vs. non-PRHC clinics.

Design: Refugees with Class B (non-communicable) tuberculosis (TB) admitted to the United States from 2010 to 2012 who were being treated at PRHC clinics were compared to those treated at non-PRHC clinics. Odds ratios (ORs) for attending a follow-up appointment, completing treatment, and time from arrival to the United States to the first TB screening test were calculated.

Results: Of the 2094 refugees who arrived in Philadelphia in 2010-2012, the Philadelphia Department of Public Health was notified of 149 who required additional evaluation for TB. Among these, 57 (38.3%) were confirmed to have LTBI, and none were diagnosed with active TB. All LTBI cases were recommended for anti-tuberculosis prophylaxis and 43 (75.4%) completed treatment. Refugees receiving care from PRHC clinics were more likely to be screened within 30 days of arrival (OR 4.70, 95%CI 2.12-10.44), attend a follow-up appointment (OR 4.53, 95%CI 1.36-16.27), and complete treatment (OR 9.44, 95%CI 2.39-37.3).

Conclusion: Refugees who attended PRHC clinics were more likely to be evaluated promptly and to complete LTBI treatment. The PRHC clinics serve as a model for communities seeking to improve refugee health care.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Age Distribution
  • Ambulatory Care Facilities
  • Antitubercular Agents / therapeutic use*
  • Child
  • Cohort Studies
  • Confidence Intervals
  • Disease Notification / statistics & numerical data
  • Female
  • Humans
  • Incidence
  • Latent Tuberculosis / diagnosis*
  • Latent Tuberculosis / drug therapy*
  • Latent Tuberculosis / epidemiology
  • Male
  • Mass Screening / methods
  • Medication Adherence / statistics & numerical data*
  • Middle Aged
  • Odds Ratio
  • Patient Compliance / statistics & numerical data
  • Pennsylvania
  • Philadelphia
  • Radiography, Thoracic / methods
  • Refugees / statistics & numerical data*
  • Retrospective Studies
  • Sex Distribution
  • Sputum / microbiology
  • Treatment Outcome

Substances

  • Antitubercular Agents