Trypanosoma cruzi infection in a Spanish liver transplant recipient

A Rodriguez-Guardado; M L González; M Rodriguez; M Flores-Chavez; J A Boga; J Gascon

doi:10.1016/j.cmi.2015.03.022

Trypanosoma cruzi infection in a Spanish liver transplant recipient

Clin Microbiol Infect. 2015 Jul;21(7):687.e1-3. doi: 10.1016/j.cmi.2015.03.022. Epub 2015 Apr 14.

Authors

A Rodriguez-Guardado¹, M L González², M Rodriguez³, M Flores-Chavez⁴, J A Boga³, J Gascon⁵

Affiliations

¹ Tropical Medicine Unit, Spain. Electronic address: azucenarodriguez@telecable.es.
² Hepatology Unit, Spain.
³ Microbiology Unit, Hospital Universitario Central de Asturias, Oviedo, Spain.
⁴ Leishmaniasis and Chagas Disease Unit, National Microbiology Center, Instituto de Salud Carlos III, Madrid, Spain.
⁵ ISGlobal, Centre for International Health Research (CRESIB), Barcelona, Spain.

PMID: 25882355
DOI: 10.1016/j.cmi.2015.03.022

Abstract

The shortage of suitable organ donors for transplantation has stimulated the use of organs from donors with transmissible infections such as Chagas disease in noninfected recipients. A case is described of liver transplantation from an anti-Trypanosoma cruzi-positive donor to a noninfected recipient who showed favorable evolution despite not having undergone preemptive therapy.

Keywords: Benznidazole; Chagas disease; evolution; liver transplant; therapy.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Chagas Disease / diagnosis*
Chagas Disease / pathology
Female
Humans
Liver Transplantation / adverse effects*
Middle Aged
Spain
Transplant Recipients*
Treatment Outcome
Trypanosoma cruzi / isolation & purification*