Prevention of congenital Chagas through treatment of girls and women of childbearing age

Mem Inst Oswaldo Cruz. 2015 Jun;110(4):507-9. doi: 10.1590/0074-02760140347. Epub 2015 May 15.

Abstract

It is currently unknown whether treatment of Chagas disease decreases the risk of congenital transmission from previously treated mothers to their infants. In a cohort of women with Chagas disease previously treated with benznidazole, no congenital transmission of the disease was observed in their newborns. This finding provides support for the treatment of Chagas disease as early as possible.

MeSH terms

  • Adolescent
  • Adult
  • Chagas Disease / drug therapy
  • Chagas Disease / parasitology
  • Chagas Disease / transmission*
  • Child
  • Cohort Studies
  • Female
  • Humans
  • Infectious Disease Transmission, Vertical*
  • Nitroimidazoles / therapeutic use*
  • Pregnancy
  • Pregnancy Complications, Parasitic* / drug therapy
  • Primary Prevention
  • Trypanocidal Agents / therapeutic use*
  • Trypanosoma cruzi
  • Young Adult

Substances

  • Nitroimidazoles
  • Trypanocidal Agents
  • benzonidazole